OPI may refer to:

Organizations

• Order of Perpetual Indulgence or Sisters of Perpetual Indulgence
• The Office of Police Integrity, Victoria, Australia

Science and technology

• Open Payment Initiative
• Ocular protection index

Places

• Opi, Abruzzo, a comune in Italy
• Opi (archaeological site), Enugu State, Nigeria

Other uses

• Over the phone interpreting
• Oral Proficiency Interview
• OPI Products, a US nail polish manufacturer
• Opi, an Igbo musical instrument
• Oremus Pro Invicem, Latin for Let us Pray for each other (see List of Latin phrases (O))

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