The Trans-Canada Highway crosses all provinces of Canada.

• Trans-Canada Highway
• Yellowhead Highway

All provincial highways in Alberta are 'Primary Highways'. They are divided into two series, and sub-series.

• 1-216 Series — core highway network
  • Hwy 1-100 — intercity ( Hwy 100 is unmarked, ex: Hwy 2)
  • Hwy 201, 216 — orbital routes (ex: Hwy 216)
• 500-986 Series — local highways
  • Hwy 500-699 — west-east routes (ex: Hwy 501)
  • Hwy 700-899 — south-north routes (ex: Hwy 881)
  • 900 and X series — potential realignments and extensions (ex: Hwy 986)

Varying between west-east and south-north routes, route numbers in British Columbia span from 1-118, except for Hwy 395 which is a counterpart of US 395. The 400 series highways were renumbered in 1973.
(ex: Hwy 97)

Provincial Trunk Highways (PTH) in Manitoba are divided into two series.

• PTH 1-199 — primary routes
  • PTH 1-89 — intercity (ex: PTH 75)
  • PTH 100, 101, 110 — loop routes (ex: Perimeter Highway)
• PR 200-699 — secondary routes

Provincial highways in New Brunswick are divided into three series.

• Route 1-99 — arterial highways (ex: Route 11)
• Route 100-199 — collector highways (ex: Route 108)
• Route 200-999 — local highways (ex: Route 275)

Provincial highways in Newfoundland and Labrador are divided into three series.

• Main highways
  • Routes 1, 210, 230, 320, 330, 340, 360, 410, 430, 480, 500, and 510
• Regional roads are numbered by region
  • Route 2-203 — Avalon Peninsula
  • Route 204-205, 230-239 — Bonavista Peninsula
  • Route 210-222 — Burin Peninsula
  • Route 301-346 — Kittiwake Coast, Fogo Island, & Twillingate
  • Route 350-371 — Exploits River Valley & Bay d'Espoir
  • Route 380-392, 410-419 — Baie Verte
  • Route 401, 420-438 — Great Northern Peninsula
  • Route 402-407, 440-490 — Western Newfoundland
  • Route 500-520 — Labrador
• Local highways are based on intersecting primary routes and numbered with extension (i.e. 210-1)

Provincial highways in Nova Scotia are divided into five series.

• 100 Series — arterial highways (ex: Hwy 102)
• Trunk Highways (ex: Trunk 4)
• Route 200-399 — collector highways (ex: Route 221)
• Scenic Routes are unnumbered
• Local roads are unnumbered

Provincial highways in Prince Edward Island are divided into three series.

• Route 1-4 — arterial highways
• Route 4-26 — collector highways
• Local highways are numbered by county
  • Route 101-199 — Prince County
  • Route 201-299 — Queens County
  • Route 301-399 — Kings County

Provincial highways in Quebec are divided into three classes. Odd numbers refer to routes that are generally perpendicular to the Saint Lawrence River. Even numbers refer to routes that are generally parallel to the Saint Lawrence River.

• Autoroutes — expressways ( Route 920 is unmarked, ex: Autoroute 20)
  • Route numbers for bypasses and spurs take on a prefix (4nn-9nn)
• 100-series — primary highways (ex: Route 138)
• Secondary routes
  • 200-series — south of the Saint Lawrence River (ex: Route 263)
  • 300-series — north of the Saint Lawrence River (ex: Route 348)

Provincial highways in Saskatchewan are divided into three series, and sub-series.

• Hwy 1-99 — primary highways (ex: Hwy 11)
• Hwy 100-399 — secondary highways which are spurs of primary highways
  • Hwy 102-167 — northern routes (ex: Hwy 106)
  • Hwy 201-271 — routes to recreational areas (ex: Hwy 211)
  • Hwy 301-397 — routes to minor communities (ex: Hwy 375)
• Hwy 600-799, 900-999 — minor highways
  • Hwy 600-699 — south-north highways
  • Hwy 700-799 — west-east highways
  • Hwy 900-999 — northern or isolated roads (ex: Hwy 999)