"Nocardia blackwellii" (Erikson 1935) Waksman and Henrici 1948
Nocardia farcinica is a species of
bacteria, once thought to be associated with
farcy, and a member of the genus Nocardia. This species is very similar in phenotype to Nocardia asteroides, to the degree that some isolates of N. asteroides were later found to be Nocardia farcinica.[3]
Pathogenicity
N. farcinica may be a causative agent of
nocardiosis[4] or of secondary infections in immunocompromised patients.[5] Strains of this species have been isolated from human brain abscesses.[6]
Genome
N. farcinica contains a 6 million
base pair genome with an average
GC content of 70.8%. A sequenced strain, IFM 10152, is also known to contain two plasmids, pNF1 pNF2. The chromosome encodes 5,674 potential protein-coding
open reading frames. This genome may have undergone numerous
gene duplication events as a result of adapting to new environments.[7]
^Torres, O. H.; Domingo, P.; Pericas, R.; Boiron, P.; Montiel, J. A.; Vázquez, G. (3 April 2000). "Infection Caused by Nocardia farcinica : Case Report and Review". European Journal of Clinical Microbiology & Infectious Diseases. 19 (3): 205–212.
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^Malincarne, Lisa; Marroni, Massimo; Farina, Claudio; Camanni, Guido; Valente, Marina; Belfiori, Barbara; Fiorucci, Stefano; Floridi, Piero; Cardaccia, Angela; Stagni, Giuliano (1 May 2002). "Primary brain abscess with Nocardia farcinica in an immunocompetent patient". Clinical Neurology and Neurosurgery. 104 (2): 132–135.
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Malla, Sailesh; Pandey, Ramesh Prasad; Kim, Byung-Gee; Sohng, Jae Kyung (22 April 2013). "Regiospecific modifications of naringenin for astragalin production in Escherichia coli". Biotechnology and Bioengineering. 110 (9): 2525–2535.
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PMID23568509.
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Toyomitsu, Sawai (April 8, 2014). "A case of community-acquired pneumonia due to influenza A virus and Nocardia farcinica co-infection". Journal of Infection and Chemotherapy. 20 (8): 506–508.
doi:
10.1016/j.jiac.2014.04.008.
PMID24855916.