NKC is a three letter abbreviation that may refer to:

• IATA airport code for Nouakchott–Oumtounsy International Airport
• National Kennel Club, all-breed dog registry in the United States
• Nat King Cole, American jazz singer/musician
• NDR-Klein-Computer, a German computer
• Northwest Kidney Centers, outpatient hemodialysis treatment center
• Natural killer cell, cell involved in the innate immune system
• National Knowledge Commission, Indian Commission set up by Manmohan Singh

This disambiguation page lists articles associated with the title NKC.
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