Names | |
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Preferred IUPAC name
Piperidine-1-carbaldehyde | |
Other names
1-Formylpiperidine
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Identifiers | |
3D model (
JSmol)
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107697 | |
ChemSpider | |
DrugBank | |
ECHA InfoCard | 100.018.170 |
EC Number |
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MeSH | N-Formylpiperidine |
PubChem
CID
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RTECS number |
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UNII | |
UN number | 2810 |
CompTox Dashboard (
EPA)
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Properties | |
C6H11NO | |
Molar mass | 113.160 g·mol−1 |
Density | 1.019 g cm−3 |
Boiling point | 222 °C (432 °F; 495 K) |
Vapor pressure | 0.01 kPa |
Hazards | |
GHS labelling: | |
Danger | |
H302, H311, H315, H319, H335 | |
P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P361, P362, P363, P403+P233, P405, P501 | |
NFPA 704 (fire diamond) | |
Flash point | 102 °C (216 °F; 375 K) |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
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N-Formylpiperidine is an organic compound with the formula C6H11NO. It is the amide of formic acid and piperidine. It can be used as a polar aprotic solvent, with better hydrocarbon solubility than other amide solvents such as dimethylformamide (DMF). [1] It has also been used to transfer the formyl group to a Grignard reagent: [2]
In some formylation reaction of alkyllithium compounds, N-formylpiperidine gives higher yields than the DMF. [3]