From Wikipedia, the free encyclopedia
Ethical protocol of the WHO
Monitored Emergency Use of Unregistered and Investigational Interventions (MEURI ) is an
ethical protocol developed by the
World Health Organization to evaluate the potential use of experimental drugs in the event of
public health emergencies .
[1]
[2]
The protocol was created by the
WHO Ebola Ethics Working Group in 2014
[3]
[4] in the context of the
2014 West Africa Ebola outbreak . The WHO recommends that the term be preferred to the term "
compassionate use " or "
expanded access " for the controlled use of unregistered treatments in public health emergency measures.
[5]
[6]
References
^ World Health Organization (WHO). (2016). Emergency use of unproven interventions outside of research [Chapter 9]. In Guidance for Managing Ethical Issues in Infectious Disease Outbreaks. World Health Organization.
https://apps.who.int/iris/handle/10665/250580 . alternative DOI:
https://doi.org/10.5281/zenodo.3715302
^
"Notes for the record: Consultation on Monitored Emergency Use of Unregistered and Investigational Interventions for Ebola Virus Disease (EVD)" (PDF) . World Health Organization. 17 May 2018. Retrieved 26 May 2018 .
^ WHO Ethics Working Group (2014). "Ethical issues related to study design for trials on therapeutics for Ebola Virus Disease: WHO Ethics Working Group meeting 20–21 October, summary of discussion". World Health Organization.
hdl :
10665/137509 .
^ Calain, Philippe (2018-01-01).
"The Ebola clinical trials: a precedent for research ethics in disasters" . Journal of Medical Ethics . 44 (1): 3–8.
doi :
10.1136/medethics-2016-103474 .
ISSN
0306-6800 .
PMC
5749307 .
PMID
27573153 .
^ Richardson, Thomas; Johnston, Andrew McDonald; Draper, Heather (2017-01-17).
"A Systematic Review of Ebola Treatment Trials to Assess the Extent to Which They Adhere to Ethical Guidelines" . PLOS ONE . 12 (1): e0168975.
Bibcode :
2017PLoSO..1268975R .
doi :
10.1371/journal.pone.0168975 .
PMC
5240928 .
PMID
28095476 .
^ Alirol, Emilie; Kuesel, Annette C.; Guraiib, Maria Magdalena; dela Fuente-Núñez, Vânia; Saxena, Abha; Gomes, Melba F. (2017-06-26).
"Ethics review of studies during public health emergencies - the experience of the WHO ethics review committee during the Ebola virus disease epidemic" . BMC Medical Ethics . 18 (1): 43.
doi :
10.1186/s12910-017-0201-1 .
ISSN
1472-6939 .
PMC
5485606 .
PMID
28651650 .