Mixed-use development is a term used for two related concepts:
- In the sense of mixed-use zoning or mixed-use planning, it is a type of urban development, urban planning and/or a zoning type that blends residential, commercial, cultural, institutional, or entertainment uses into one space, where those functions are to some degree physically and functionally integrated, and that provides pedestrian connections.    Mixed-use development may be applied in new real estate development projects in a city or suburb, or may apply to a single building, existing or new neighborhood, or in zoning policy across an entire city or other political unit.
- In the sense of a mixed-use complex, mixed-use project, etc., a mixed-use development refers to "a development" — a building, complex of buildings, or new district of a community that is developed for mixed-use by a private developer, (quasi-) governmental agency, or a combination thereof. A mixed-use development may be new construction, reuse of an existing building or brownfield site, or a combination.
Traditionally, human settlements have developed in mixed-use patterns. However, with industrialisation as well as the invention of the skyscraper, governmental zoning regulations were introduced to separate different functions, such as manufacturing, from residential areas. In the United States, the heyday of separate-use zoning was after World War II, but since the 1990s, mixed-use zoning has once again become desirable as the benefits are recognized. 
In most of Europe, government policy has encouraged the continuation of the city center's role as a main location for business, retail, restaurant, and entertainment activity, unlike in the United States where zoning actively discouraged such mixed use for many decades. As a result, much of Europe's central cities are mixed use "by default" and the term "mixed-use" is much more relevant regarding new areas of the city, when an effort is made to mix residential and commercial activities – such as in Amsterdam's Eastern Docklands – rather than separate them.  
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Mixed-use development allows the creation of plazas and outdoor corridors between buildings and sidewalks. Street facing facades have a maximum setback to how much space is allocated for pedestrians to gather in. Landscaping another feature in outdoor spaces allow trees and plants to grow on buildings vertically rather than being faced out in a front row. 
Mixed-use in centers that have increased in population density has allowed people to access places through public transit and has helped encourage walking, biking, and cycling to places of work and errands. Transportation has played a role in mitigating climate change by reducing congestion on roads and building up freight movement for goods and services. With street-level design in place in cities like Boston, Seattle, and Denver Mixed-uses allowed the designs of pedestrian walkways, plazas, and eye distances to shops and workplaces. This in turn has reduced parking lots in alleyways and garages. 
Expanded use of mixed-use zoning and mixed-use developments may be found in a variety of contexts, such as the following (multiple such contexts might apply to one particular project or situation): 
- as part of smart growth planning strategies
- in traditional urban neighborhoods, as part of urban renewal and/or infill, i.e. upgrading the buildings and public spaces and amenities of the neighborhood to provide more and/or better housing and a better quality of life - examples include Barracks Row in Washington, D.C. and East Liberty, Pittsburgh
- in traditional suburbs, adding one or more mixed-use developments to provide a new or more prominent "downtown" for the community - examples include new projects in downtown Bethesda, Maryland, an inner suburb of Washington, D.C., and the Excelsior & Grand complex in St. Louis Park, Minnesota, an inner suburb of Minneapolis
- greenfield developments, i.e. new construction on previously undeveloped land, particularly at the edge of metropolitan areas and in their exurbs, often as part of creating a relatively denser center for the community – an edge city, or part of one, zoned for mixed use, in the 2010s often labeled "urban villages". Examples include Avalon in Alpharetta, Georgia and Halcyon in Forsyth County, Georgia, at the edge of the Atlanta metropolitan area
- Repurposing of shopping malls and intensification of development around them, particularly as many shopping malls' retail sales, and ability to rent space to retailers, decrease as part of the 2010s retail apocalypse
Any of the above contexts may also include parallel contexts such as:
- Transit-oriented development - for example in Los Angeles and San Diego where the cities made across-the-board zoning law changes permitting denser development within a certain distance of certain types of transit stations, with the primary aim of increasing the amount and affordability of housing 
- Older cities such as Chicago and San Francisco have historic preservation policies that sometimes offer more flexibility for older buildings to be used for purposes other than what they were originally zoned for, with the aim of preserving historic architecture 
Plans promoting mixed-use development or zoning claim that it will achieve numerous benefits; for example the Director of Smart Growth for the State of New York claims that mixed-use development aims to achieve:  
- greater housing variety and density, more affordable housing (smaller units), life-cycle housing (starter homes to larger homes to senior housing)
- more walkable neighborhoods
- reduced distances between housing, workplaces, retail businesses, and other amenities and destinations
- better access to fresh, healthy foods (as food retail and farmers markets can be accessed on foot/bike or by transit)
- more compact development, land-use synergy (e.g. residents provide customers for retail which provide amenities for residents)
- stronger neighborhood character, "sense of place", community identity
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Some of the more frequent mixed-use scenarios in the United States are: 
- Neighborhood commercial zoning – convenience goods and services, such as convenience stores, permitted in otherwise strictly residential areas
- Main Street residential/commercial – two to three-story buildings with residential units above and commercial units on the ground floor facing the street
- Urban residential/commercial – multi-story residential buildings with commercial and civic uses on ground floor
- Office convenience – office buildings with small retail and service uses oriented to the office workers
- Office/residential – multi-family residential units within office building(s)
- Shopping mall conversion – residential and/or office units added (adjacent) to an existing standalone shopping mall
- Retail district retrofit – retrofitting of a suburban retail area to a more village-like appearance and mix of uses
- Live/work – residents can operate small businesses on the ground floor of the building where they live
- Studio/light industrial – residents may operate studios or small workshops in the building where they live
- Hotel/residence – mix hotel space and high-end multi-family residential
- Parking structure with ground-floor retail
- Single-family detached home district with standalone shopping center
One of the earliest cities to adopt a policy on mixed-use development is Toronto. The local government first played a role in 1986 with a zoning bylaw that allowed for commercial and residential units to be mixed. At the time, Toronto was in the beginning stages planning a focus on developing mixed-use development due to a growing popularity of more social housing . The law has since been updated as recently as 2013, refining much of its focus outside the downtown area which has been amalgamated into the main city since 1998. With the regulations in place, the city has oversaw the development of high-rise condominiums throughout the city with amenities and transit stops nearby. Toronto case of developing Mixed-uses has expand to encompass other North American cities in Canada and The United States to bring in similar changes. 
One example of a Toronto mixed-use development is Mirvish Village  by architect Gregory Henriquez. Located at Bloor and Bathurst Street, a significant intersection in Toronto, portions of the Mirvish Village project site are zoned as "commercial residential" and others as "mixed commercial residential."  Within the City of Toronto's zoning by-laws, commercial residential includes "a range of commercial, residential and institutional uses, as well as parks."  Mirvish Village's programmatic uses include rental apartments, a public market, and small-unit retail,  while also preserving 23 of 27 heritage houses on site.  The project is notable for its public consultation process, which was lauded by Toronto city officials.  Architect Henriquez and the developer had previously collaborated on mixed-use projects in Vancouver, British Columbia, including the successful Woodward's Redevelopment. 
In the United States, the Environmental Protection Agency (EPA) collaborates with local governments by providing researchers developing new data that estimates how a city can be impacted by mixed-use development. With the EPA putting models in the spreadsheet, it makes it much easier for municipalities, and developers to estimate the traffic, with Mixed-use spaces. The linking models also used as a resource tool measures the geography, demographics, and land use characteristics in a city. The Environmental Protection Agency has conducted an analysis on six major metropolitan areas using land usage, household surveys, and GIS databases. States such as California, Washington, New Mexico, and Virginia have adopted this standard as statewide policy when assessing how urban developments can impact traffic. Preconditions for the success of mixed-use developments are employment, population, and consumer spending. The three preconditions ensure that a development can attract quality tenants and financial success. Other factors determining the success of the Mixed-use development is the proximity of production time, and the costs from the surrounding market. 
Mixed-use zoning has been implemented in Portland, Oregon since the early 1990s, when the local government wanted to reduce the then-dominant car-oriented development style. Portland's light rail system MAX encourages the mixing of residential, commercial, and work spaces into one zone. With this one-zoning-type planning system, the use of land at increased densities provides a return in public investments throughout the city. Main street corridors provide flexible building heights and high density uses to enable "gathering places". 
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- Media related to Mixed-use developments at Wikimedia Commons