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American behavioral and psychiatric geneticist
Matthew C. Keller is an American behavioral and psychiatric geneticist. He is the Director of the
Institute for Behavioral Genetics and a professor in the Department of Psychology and Neuroscience at the
University of Colorado Boulder.
[1] He is known for his criticism of the
candidate gene approach
[2]
[3]
[4] and for development of approaches in
quantitative genetics.
[5]
[6]
References
-
^
"Matthew C Keller's Home Page". www.matthewckeller.com. Retrieved 19 February 2019.
-
^ Duncan, Laramie E.; Keller, Matthew C. (November 2011).
"A Critical Review of the First 10 Years of Candidate Gene-by-Environment Interaction Research in Psychiatry". American Journal of Psychiatry. 168 (10): 1041–1049.
doi:
10.1176/appi.ajp.2011.11020191.
ISSN
0002-953X.
PMC
3222234.
PMID
21890791.
-
^ Border, Richard; Johnson, Emma C.; Evans, Luke M.; Smolen, Andrew; Berley, Noah; Sullivan, Patrick F.; Keller, Matthew C. (May 2019).
"No Support for Historical Candidate Gene or Candidate Gene-by-Interaction Hypotheses for Major Depression Across Multiple Large Samples". American Journal of Psychiatry. 176 (5): 376–387.
doi:
10.1176/appi.ajp.2018.18070881.
ISSN
0002-953X.
PMC
6548317.
PMID
30845820.
-
^ Johnson, Emma C.; Border, Richard; Melroy-Greif, Whitney E.; de Leeuw, Christiaan A.; Ehringer, Marissa A.; Keller, Matthew C. (November 2017).
"No Evidence That Schizophrenia Candidate Genes Are More Associated With Schizophrenia Than Noncandidate Genes". Biological Psychiatry. 82 (10): 702–708.
doi:
10.1016/j.biopsych.2017.06.033.
PMC
5643230.
PMID
28823710.
-
^ Haplotype Reference Consortium; Evans, Luke M.; Tahmasbi, Rasool; Vrieze, Scott I.; Abecasis, Gonçalo R.; Das, Sayantan; Gazal, Steven; Bjelland, Douglas W.; de Candia, Teresa R.; Goddard, Michael E.; Neale, Benjamin M. (May 2018).
"Comparison of methods that use whole genome data to estimate the heritability and genetic architecture of complex traits". Nature Genetics. 50 (5): 737–745.
doi:
10.1038/s41588-018-0108-x.
ISSN
1061-4036.
PMC
5934350.
PMID
29700474.
-
^ Keller, Matthew C. (January 2014).
"Gene × Environment Interaction Studies Have Not Properly Controlled for Potential Confounders: The Problem and the (Simple) Solution". Biological Psychiatry. 75 (1): 18–24.
doi:
10.1016/j.biopsych.2013.09.006.
PMC
3859520.
PMID
24135711.
External links