This is a list of the Swiss Hitparade number-one hits of 2021.
Swiss charts
| Issue date | Song | Artist | Album | Artist |
|---|---|---|---|---|
| 3 January | " Jerusalema (Remix)" | Master KG featuring Burna Boy and Nomcebo Zikode | Power Up | AC/DC |
| 10 January | ||||
| 17 January | Splitter aus Glück | Daniela Alfinito | ||
| 24 January | Unplugged | Pegasus | ||
| 31 January | ||||
| 7 February | Hautnah | Vincent Gross | ||
| 14 February | Medicine at Midnight | Foo Fighters | ||
| 21 February | Pass | Dodo | ||
| 28 February | " Wellerman" | Nathan Evans | Adios amigos – Live @ Wacken | Krokus |
| 7 March | The Ghost Orchestra | The Ghost Orchestra | ||
| 14 March | 2021: À côté de vous | Les Enfoirés | ||
| 21 March | Mai | Kunz | ||
| 28 March | Chemtrails over the Country Club | Lana Del Rey | ||
| 4 April | The Bitter Truth | Evanescence | ||
| 11 April | Abentüür Monschterschlucht | Schwiizergoofe | ||
| 18 April | Sing meinen Song - Das Schweizer Tauschkonzert - Volume 2 | Various artists | ||
| 25 April | Californian Soil | London Grammar | ||
| 2 May | Sing meinen Song - Das Schweizer Tauschkonzert - Volume 2 | Various artists | ||
| 9 May | Stay High | Ufo361 | ||
| 16 May | Heimspiel | Blay | ||
| 23 May | Sampler 5 | 187 Strassenbande | ||
| 30 May | " Tout l'univers" | Gjon's Tears | Earth, Wind & Feiern | Jan Delay |
| 6 June | " Good 4 U" | Olivia Rodrigo | Reprise | Moby |
| 13 June | Hardware | Billy Gibbons | ||
| 20 June | Neue Welt | Azet | ||
| 27 June | " Beggin'" | Måneskin | Bahama Sunshine | Calimeros |
| 4 July | HeimatLiebe | Kastelruther Spatzen | ||
| 11 July | Aqua | Luciano | ||
| 18 July | " Bad Habits" | Ed Sheeran | Freiheit | Die Amigos |
| 25 July | Zukunft | RAF Camora | ||
| 1 August | Asozialer Marokkaner | Farid Bang | ||
| 8 August | Happier Than Ever | Billie Eilish | ||
| 15 August | ||||
| 22 August | Herzfarben | Francine Jordi | ||
| 29 August | Happier Than Ever | Billie Eilish | ||
| 5 September | Alles was du brauchst | Beatrice Egli | ||
| 12 September | " Don't Shut Me Down" | ABBA | Senjutsu | Iron Maiden |
| 19 September | "Bad Habits" | Ed Sheeran | Gold – Das Jubiläumsalbum mit allen Hits und neuen Liedern | Heimweh |
| 26 September | " Love Nwantiti" | CKay featuring Joeboy and Kuami Eugene | 10 | Schwiizergoofe |
| 3 October | Dunkel | Die Ärzte | ||
| 10 October | Zukunft | RAF Camora | ||
| 17 October | Wenn die Kälte kommt | Santiano | ||
| 24 October | " Easy on Me" | Adele | Rausch | Helene Fischer |
| 31 October | Handwärch | Gölä and Trauffer | ||
| 7 November | " Shivers" | Ed Sheeran | = | Ed Sheeran |
| 14 November | Voyage | ABBA | ||
| 21 November | ||||
| 28 November | "Easy on Me" | Adele | 30 | Adele |
| 5 December | ||||
| 12 December | " Merry Christmas" | Ed Sheeran and Elton John | ||
| 19 December | " All I Want for Christmas Is You" | Mariah Carey | ||
| 26 December | Voyage | ABBA |