The weekend has come and Fran is going to stay at his father's house, Paco already has a plan to go out with his girlfriend Miranda, so Fran takes advantage and invites her friend Lola to sleep. The next morning everyone comes for breakfast.

Paco spends a great weekend next to his son Fran and his girlfriend Miranda, until Rocío his ex-wife arrives to stay with them, since a mouse has been sent to her house.

Fran is doing poorly in school and needs some regularization classes, so the weekend that he stays at his father's house, takes advantage to take a little class in his room and a spectacular teacher.

Fran goes camping and Paco wants to spend a romantic weekend with Miranda, but she has other plans, a French friend has arrived in Mexico and has invited him to stay in the apartment.

It's Miranda's birthday and they go out to party, as the night goes by, Paco feels bad and leaves her there. The next morning Miranda appears in the door drunk and with a very peculiar aroma.

Fran's regular teacher shows up surprisingly in the apartment, only carrying a suitcase and a child.

Fran asks his dad why he divorced his mother, he tells his version of the story, corrected and increased and even Mijares, the famous singer comes out muddy.

Fran and her friend have planned to bring a student exchange home, but Paco flatly refuses to receive her, until he sees Bruna.

Paco has a new girlfriend, Montse and for their first weekend together, she takes her sister Vero, who is very depressed because she ended her relationship with her boyfriend.

Paco discovers a pregnancy test in the trash can. He thinks it belongs to Lola, Montse, or Toña.

Paco is again single and very depressed, so Fran suggests to find a new girlfriend online. Paco is very surprised to enter a site and see the photo of Maribel, an old love.

Fran resorts to one of his cell phone apps to meet a new friend and invite her to sleep at his dad's house. A few hours later Xóchitl arrives, a young woman of spectacular body and of dubious origin.

Paco is very depressed by the robbery to his apartment and asks Rocío to borrow her furniture. New neighbors have arrived to the building and Fran is trapped in the elevator with one of them.

Paco recovers the furniture of his house, but Toña is inconsolable because her perfume brought from Oaxaca does not appear.

Fofo, the brother of Paco has arrived to visit Mexico, without wife and with a singular couple.

Macarena is about to get married and has nowhere to make her bachelorette party, so Paco very kindly offers his department for the celebration.

After the bachelorette party, Paco's neighbors are very upset, so they want to evict him from the building.

Pedro, Paco's best friend is about to lose his marriage for cheating on his wife. Paco could save his life.

Toña has left the house and Brayan Danielle has recommended her aunt, Doña Lucha, to help out with house chores.

Paco goes on a trip and Fran finds the perfect opportunity to earn a few dollars, he rents his dad's apartment to some elderly people for the weekend, a few hours later Paco's flight is canceled.

Fran has just met Karime and falls madly in love with her, only that there is a small problem, Karime is getting married next weekend.

Paco accompanies Fran to the wedding of Karime and there he meets Emilia, a former student who failed at the university.

Paco is fired from the university because of the scandal that has been generated by Emilia and all his women claim him.

Rocío has decided to take his son Fran to therapy, but surprisingly she learns that he loves older women.

Paco returns with his ex-girlfriend Miranda and takes her to live in his house, everything is going well, until Lorena arrives and the world collapses.

Lorena, Paco's pretty lover, wants to blackmail him with a false pregnancy. Paco enters in crisis, returns to take and bottoms.

Paco organizes a party to celebrate his singleness; the next morning dawns with Lauris the neighbor, who takes the adventure very seriously, to the degree of bringing her parents to meet her future husband.

Rocío goes into depression because she is abandoned by Victor, her boyfriend. She asks Paco for help, who sponsors a trip to India to find herself again.

Rosario, the ex-sister in law of Paco, takes the administration of the building, puts everyone in trouble by setting very strict and severe rules.

Fed up with Rosario, Paco organizes a neighborhood election to change the administration of the building. The candidates are Rosario, Paco, and Toña, the representative of town.

Paco joins a gym and meets Lety, a beautiful fitness instructor, who is vegan. He agrees to a rigorous diet and exercises that are killing him.

Fran has an affair with a lady, whom he meets in the supermarket. Meanwhile, Paco receives the unexpected visit of a Russian stewardess with whom he entered the Club of 33 Thousand Feet.

Fran returns from his generation trip with a story, he got married in Havana with Yusnavis, a spectacular Cuban, whom he has brought to live in Mexico.

Paco returns to give architecture classes and meets Mónica, a beautiful student with whom he initiates a romance, this one is interrupted when in the apartment appears Samuel, the father of Mónica.

Toña says that her parents never gave her a quinceañera. After a long debate, Rosario presses Paco to sponsor the late quinceañera celebration of Toña.

After a long planning comes the day of the celebration of the quinceañera of Toña; what at first starts as a traditional and emotional party, ends in a true pandemonium.

Paco threatens to spend the weekend outside of Mexico, so Fran and El Borrego rent the apartment for the filming of a movie.

Fran meets Sheyla in Tinder, an attractive and mature "vintage actress", whom he invites to dinner at the apartment. When she arrives, he meets a woman much older than him, but it's too late.

Paco and Toña are in serious problems. They do not know what to do with Sheyla's body, that appeared dead on the sofa of the house.

Beto, Paco's cousin, arrives at the apartment asking for to stay, since his wife, Julia, caught him in making a move and made him leave his house.

Beto is a charming slob. Paco and Fran warn Toña that Beto is cheating on her. But she thinks they say that because they're jealous.

Toña’s family arrives and as she told them something different from the reality, Paco has to pretend to be her boyfriend and Fran plays the role of butler.

Paco arrives at the apartment with Meche, a friend, and she proposes to go to a massive nude in the pyramids of Teotihuacan, for some photos. She promises that it is a unique experience. But Toña is the only one who is not encouraged.

Paco's nephew, Jacobito, comes to spend a few days with them, since he is on vacation. But he does not let Paco be alone with his girlfriend Mayra, and he even sleeps with them.

Paco arrives scared at home with his friend Cassandra and tells Toña and Fran that the bank where he made a deposit was assaulted. But it turns out that Cassandra is the assailant.

Fran brings a new girlfriend to the apartment, Tatiana, an airplane pilot who knows how to fix a television and likes soccer. But Toña puts in Paco's head that the girl is a man and he, astonished, asks her not to leave them alone.

Weird things happen in the Cossio home and everything indicates that the culprit is an old doll. Paco and Fran talk to their friends about what is happening that has them so scared.

After a night of partying, Fran's mother comes to visit, but he almost does not recognize her because of how changed she is. She went to a retreat in India and now uses a backpack and has dreadlocks. She asks them to let her spend a few days with them.

Rocío's boyfriend left her and she is desperate. But Fran puts order and scolds his parents, sends his mom to take a shower and tells Paco not to drink alcohol again.

Paco gets upset with Renata, the famous Youtuber known as Rex, with whom he is going out with, because she uploaded videos of him to social networks and the comments that people make are not very to his liking.

Beto comes to visit with four tickets for a concert and Paco must get someone to go with.

Paco fires Toña and he, along with Beto, Fran and Brayan Danielle will do a casting to choose the woman who can replace her, but Toña could return with a well-deserved increase in salary.

Beto goes to live in Paco's building and proposes to build a pool. Horcasitas is convinced until she meets Fran, whom she exploits in order to give permission for their project.

Fran invites Luciana to the apartment, but she will not go alone. He must sacrifice himself as long as he spends more time with her.

Paco's father plans to stay and live with his son and grandson, but to please him is impossible, so Paco asks his mother for help, but she makes it a condition that his father apologizes to her.

Toña and Fran receive the invitation to Miranda's wedding and Paco will suffer from the news, but in the end he will do everything not to lose his love.

Paco and Miranda decide to go to couples therapy to finally achieve a healthy and stable relationship, but the therapist Sylvana Mora is only interested in Fran.

After being drunk with Miranda, Paco falls, hitting his head tremendously. When he wakes up he seems to be someone else.

Josefa is the Spanish woman who will try to conquer Paco, even over Miranda, and who will surprise everyone by discovering her true intentions.

Seeing the high school yearbook, Paco and Beto decide to meet up with some of their former classmates, so they will have a party in the apartment.

Brayan Daniel discovers that he has won the lottery and with the money he plans to carry out many dreams and plans.

A party is organized for Paco to forget about Miranda, but when Rocío arrives she mistakes it for a surprise party for her for her birthday, which everyone ends up celebrating in their own way.

After having spent the night together, Rocío arrives with the news that she and Paco will give Fran a little brother.

Rocío moves to Paco's house because, according to her, she requires rest and care due to an alleged high-risk pregnancy. She takes advantage of this to exploit Paco, Fran and Toña and get her family back.

Fran finds his true calling in painting and enrolls in classes with an attractive teacher. He seems to be advancing fast and must hire a professional model who will be very expensive for Paco.

Clementina, Toña's cousin, comes to live in the apartment. She is an all-seeing psychic and will use her gifts to solve everyone's life, hiding her true intentions.

The result of the final between Cruz Azul and América will depress Paco, but his great friend Emilio will teach him a lesson.

Melina, a former student of Paco, will arrive to confess that she got divorced because she is in love with him and wants them to start a family. Only a crazy idea from Toña can save him.

Fran joins Los Cascabelillos, an alternative indie rock band. When they think of rehearsing in the apartment, Paco is furious, although someone will make him change his mind.

Fran and El Borrego invite an Italian exchange student to stay in their apartment all summer long thinking that it is a woman.

Fran and El Borrego make a short film for university that has Toña and Brayan Dannielle as protagonists.

Miranda sues Paco for loss of time during their relationship. Beto recommends a very peculiar lawyer to Paco to face her in court.

Toña and Brayan Dannielle have a strong argument and break up. However, Pascal, Toña's French boyfriend, returns to make her forget her sadness, but Brayan is not willing to lose her.

Toña is undecided, as she doesn't know whether to marry Brayan Dannielle or Pascal, but after clearing her mind she celebrates her bachelorette party.

After the excesses of their bachelor parties, Toña and Brayan Danielle's wedding day arrives, but it is in danger of not taking place.

Toña goes partying in Acapulco to forget Brayan. Brayan wants to get Toña back, but to return to her he must jump from La Quebrada.

Brayan jumps from La Quebrada to obtain Toña's forgiveness. Everything gets complicated when Irmita visits a recovering Brayan.

Paco believes that Miranda will come to him to apologize for her infidelity in Acapulco, but she confesses that she is pregnant.

Fran and El Borrego want to go to live in New York on exchange, but one of them will be rejected. The beautiful Jeanine will advise them and will dazzle Paco.

The apartment feels empty without Fran, but El Borrego comes to occupy Fran's space and causes a lot of problems.

After not being with Fran and not having received Paco's pension, Rocío plans to move into the apartment for a while, but is surprised to learn that El Borrego is already living there.

Paco pushes Borrego to find a job and in the chosen job he falls in love with a beautiful DJ.

Paco has an intense relationship with Simone, which causes him health problems due to so much partying.

Paco fails in intimacy with Simone and his cousin Beto recommends an urologist. El Borrego becomes Laura's boyfriend.

Paco stalks Simone, who has a gig in Tulum, and makes a scene of jealousy when she returns despite Toña's advice.

Macedonio will be a congressman and now he starts flirting with Toña, but Brayan Danielle is ready to separate them.

Macedonio retaliates against Paco, Toña, Brayan and El Borre, forcing them to make a truce.

El Borre convinces Paco and Brayan Danielle to get tattoos of their significant others to convince them to get back together.

Looking to get rid of Simone's tattoo, Paco meets Mila, who will take him and Borrego to a secret cult of women.

Toña returns from a maids' convention and brings Magali, a Cuban colleague, as an exchange student.

Toña and El Borre try to find a girlfriend for Paco with a matchmaker.

Paco wakes up with Julieta, but then makes a jealousy scene and Toña helps him apologize to her.

Paco's friend Alushe asks him for asylum after being left with nothing. Toña and Borre advise Alushe to become a tiktoker or stand-up comedian.

Paco decides to start a polyamorous relationship with Mary and Kenya, friends of Borrego.

Fran returns from New York with several surprises. Upon his return, everyone prepares a party for him.

Fran receives a visit from New York, his boyfriend Ryan.

Paco sends Fran to Silvana, who remembers his romantic past. Meanwhile, Toña thinks she is pregnant.

Toña finally says yes to Brayan Danielle at the altar and father Memo takes the opportunity to be very close to Rocío.

Fran says goodbye to return to New York with Ryan. Meanwhile, Paco and Rocio give each other another chance to be together.

Paco receives a visit from Julie, an ex-girlfriend, who tells tells him that 18 years ago she had his son, Lucas. Paco agrees let Lucas stay at his house until he finds out whether or not he is his son.

Rocío suspects that Paco cheated on her while they were still married. Lucas and Paco take a DNA test.

Paco hires a mover to take Rocío's things, who turns out to be Toña's ex-boyfriend.

A foreign friend of Fran's arrives to spend a few days in the apartment after having been deported and immediately forms a close relationship with Lucas.

Toña discovers that Brayan opened a profile on Tinder, so she pretends to be someone else to catch him.

Paco tells that he was a soccer player and in a match he gets hurt, after which Moisés Muñoz reveals the whole truth, but also sends him to a physiotherapist with whom he falls in love at first sight.

Paco is going out with Joss, but his jealousy, confusing the professional with the personal, will cause him to fail again in love.

Lucas decides to drop out of college and pursue his dream, so he becomes Brayan Danielle's manager and gets him into boxing.

Isabela, a friend of Lucas, tells Paco that he should take better care of his physique, so he decides to get botox but has an unexpected outcome.

Brayan and Toña go to the wake of his cousin Natas' grandmother, but on their way back they bring a spirit from the cemetery.

Everyone seems to have forgotten Toña's birthday, but they make it up to her with a party where everything gets out of control.