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The native form of this personal name is Qi Lei. This article uses Western name order when mentioning individuals.
Lei Stanley Qi
Born
Qi Lei (亓磊)

Shandong, China
NationalityChinese
Alma mater
Known for CRISPRi, dCas9， CRISPR imaging，CRISPR-GO
Awards
Scientific career
Fields Genome engineering, Synthetic Biology
Institutions Stanford, Chemical and Systems Biology
Academic advisors Adam Arkin, Jennifer Doudna
Website

Lei "Stanley" Qi ( Chinese: 亓磊; pinyin: Qí Lěi) is an associate professor in the department of bioengineering, and the department of chemical and systems biology at Stanford University. Qi led the development of the first catalytically dead Cas9 lacking endonuclease activity (dCas9), which is the basis for CRISPR interference (CRISPRi). His laboratory subsequently developed CRISPR-Genome Organization (CRISPR-GO).

Qi is a co-inventor of the University of California patent on the CRISPR gene-editing technology.

Early life and education

Qi obtained his B.S. in physics and math from Tsinghua University, [1] China, Master in physics from UC Berkeley, and PhD in bioengineering from UC Berkeley. [2] During his PhD work at Berkeley, he studied synthetic biology with Adam Arkin, and was the first to explore engineering the CRISPR for targeted gene editing and gene regulation with Jennifer Doudna. [3] After PhD, he performed independent research work as a faculty fellow at UCSF. [4] He joined the Stanford faculty in 2014. [5] [6] [7] [8] [9] [10] [11]

Award

Qi has won awards, including NIH Director's Early Independence Award, [12] Pew Biomedical Scholar, [13] and Alfred. P. Sloan Fellowship. [14]

References

  1. ^ "Tsinghua alumni won the 2017 Sloan Research Award". Tsinghua University News. Retrieved 24 February 2017.
  2. ^ "BioE Rising Star Seminar". berkeley bioengineering. Retrieved 11 April 2018.
  3. ^ Greenwood, D.; O'Grady, F. (2016). "Cell scientist to watch – Lei Stanley Qi" (PDF). Cell Science. 129 (3): 303–9. PMC  2041082. PMID  182196.
  4. ^ "Stanley Lab in UCSF".
  5. ^ "Stanley Lab in Stanford".
  6. ^ Qi, LS*; Larson, M. H.; Gilbert, L. A.; Doudna, J. A.; Weissman, J. S.; Arkin, A. P.; Lim, W. A. (2013). "Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression". Cell. 152 (5): 1173–83. doi: 10.1016/j.cell.2013.02.022. PMC  3664290. PMID  23452860.
  7. ^ Gilbert, LA; Larson, MH; Morsut, L; Liu, Z; Brar, GA; Torres, SE; Stern-Ginossar, N; Brandman, O; Whitehead, EH; Doudna, JA; Lim, WA; Weissman, JS; Qi, LS (2013). "CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes". Cell. 154 (2): 442–51. doi: 10.1016/j.cell.2013.06.044. PMC  3770145. PMID  23849981.
  8. ^ Dominguez, AA; Lim, WA; Qi, LS (2016). "Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression". Nat Rev Mol Cell Biol. 17 (1): 5–15. doi: 10.1038/nrm.2015.2. PMC  4922510. PMID  26670017.
  9. ^ Wang, H; Xu, X; Nguyen, CM; Liu, Y; Gao, Y; Lin, X; Daley, TP; Kipniss, NH; La Russa, M; Qi, LS* (2018). "CRISPR-Mediated Programmable 3D Genome Positioning and Nuclear Organization". Cell. S0092-8674 (18): 31185–1. doi: 10.1016/j.cell.2018.09.013. PMC  6239909. PMID  30318144.
  10. ^ Chen, B; Gilbert, LA; Cimini, BA; Schnitzbauer, J; Zhang, W; Li, GW; Park, J; Blackburn, EH; Weissman, JS; Qi, LS; Huang, B (2014). "Dynamic imaging of genomic loci in living human cells by an optimized CRISPR/Cas system". Cell. S0092-8674 (18): 31185–1. doi: 10.1016/j.cell.2013.12.001. PMC  3918502. PMID  24360272.
  11. ^ Du, D; Roguev, A; Gordon, DE; Chen, M; Chen, SH; Shales, M; Shen, JP; Ideker, T; Mali, P; Qi, LS; Krogan, NJ (2017). "Genetic interaction mapping in mammalian cells using CRISPR interference". Nat Methods. 14 (6): 577–580. doi: 10.1038/nmeth.4286. PMC  5584685. PMID  28481362.
  12. ^ "NIH Director's Early Independence Award Recipients 2013 Awardees". NIH.
  13. ^ "Pew Biomedical Scholars". Pew.
  14. ^ "Sloan Foundation Past Fellows". Sloan Foundation Web.

External links

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