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Professor of chemistry and biochemistry
Joan Blanchette Broderick is a professor of chemistry and biochemistry at
Montana State University known for her work on
bioinorganic chemistry , especially the chemistry of iron-sulfur interactions. She was elected a member of the
National Academy of Sciences in 2022.
[1]
Education and career
Broderick has an undergraduate degree from
Washington State University , and an M.S. and a PhD from
Northwestern University . Following her Ph.D., she was a postdoc at
Massachusetts Institute of Technology and then an assistant professor at
Amherst College . She held a faculty position at
Michigan State University before moving to Montana in 2005.
[2]
She has been recognized as a Saltman Lecturer and Women in Science Distinguished Professor at Montana State University.
[3] In 2019, Broderick received the Alfred Bader Award in Bioinorganic or Bioorganic Chemistry from the
American Chemical Society .
[4]
Research
She has contributed to
bioinorganic chemistry often with a focus on
iron-sulfur proteins , including the
radical SAM enzymes.
[5] Her research also includes investigations into
hydrogenase where she defines the assembly of the enzymes into functional units.
[6]
[7]
Selected publications
Mulder, David W.; Boyd, Eric S.; Sarma, Ranjana; Lange, Rachel K.; Endrizzi, James A.; Broderick, Joan B.; Peters, John W. (May 2010). "Stepwise [FeFe]-hydrogenase H-cluster assembly revealed in the structure of HydAΔEFG". Nature . 465 (7295): 248–251.
Bibcode :
2010Natur.465..248M .
doi :
10.1038/nature08993 .
PMID
20418861 .
S2CID
1990191 .
Broderick, Joan B.; Duffus, Benjamin R.; Duschene, Kaitlin S.; Shepard, Eric M. (23 April 2014).
"Radical S -Adenosylmethionine Enzymes" . Chemical Reviews . 114 (8): 4229–4317.
doi :
10.1021/cr4004709 .
PMC
4002137 .
PMID
24476342 .
References
^
"2022 NAS Election" .
^
"People" . Broderick Research Group . 2017-10-09. Retrieved 2021-10-07 .
^
"Joan Broderick - Chemistry and Biochemistry - Montana State University" . www.chemistry.montana.edu .
^
"2019 ACS National Award winners" . Chemical & Engineering News . Retrieved 2019-01-22 .
^ Broderick, J. B.; Duffus, B. R.; Duschene, K. S.; Shepard, E. M., "Radical S-Adenosylmethionine Enzymes", Chemical Reviews 2014, volume 114, 4229-4317. 10.1021/cr4004709
^ Shepard, Eric M.; McGlynn, Shawn E.; Bueling, Alexandra L.; Grady-Smith, Celestine S.; George, Simon J.; Winslow, Mark A.; Cramer, Stephen P.; Peters, John W.; Broderick, Joan B. (2010-06-08).
"Synthesis of the 2Fe subcluster of the [FeFe]-hydrogenase H cluster on the HydF scaffold" . Proceedings of the National Academy of Sciences . 107 (23): 10448–10453.
Bibcode :
2010PNAS..10710448S .
doi :
10.1073/pnas.1001937107 .
ISSN
0027-8424 .
PMC
2890834 .
PMID
20498089 .
^ Peters, John W.; Broderick, Joan B. (2012-07-07).
"Emerging Paradigms for Complex Iron-Sulfur Cofactor Assembly and Insertion" . Annual Review of Biochemistry . 81 (1): 429–450.
doi :
10.1146/annurev-biochem-052610-094911 .
ISSN
0066-4154 .
PMID
22482905 .
External links