The International Society for Extracellular Vesicles (ISEV) is an international scientific organization that focuses on the study of extracellular vesicles (EVs). ^[1] These membrane-bound particles are released from all known cells and include exosomes, ectosomes, exophers, oncosomes, and more. Established in 2011, the society is a nonprofit organization. It is governed by an executive committee. The current president is Buzás Edit. Previous presidents were Clotilde Théry (2018-2022), Andrew Hill (2016-2018) and founding president Jan Lötvall (2011-2016). The society's journals are the Journal of Extracellular Vesicles and the Journal of Extracellular Biology. ^[2] ISEV also publishes the international consensus guidelines for EV studies, the "Minimal information for studies of EVs" (MISEV). ^{[3] [4]}

Meetings

As part of its mission to promote scientific research and education, the society hosts an annual meeting and educational event as well as numerous workshops on defined EV-related topics. The society also co-sponsors or endorses related events.

Workshops and scientific seminars

ISEV workshops began with a meeting on extracellular RNA ( New York City, 2012), ^{[5] [6] [7]} and continue to include one to two meetings per year. During widespread restrictions on in-person meetings during the COVID-19 pandemic, ISEV introduced the "Extracellular Vesicle Club," a weekly virtual event featuring presentations and moderated discussion of scientific publications. ^[8]

Endorsed or co-sponsored events

The society has directly or indirectly supported EV-related events around the world. These include meetings of the UK, French, and Spanish and Portuguese EV Societies (GEIVEX), a course of the European Molecular Biology Laboratory, Keystone Symposia (2016 and 2018), ^[9] Gordon Research Conferences (2016, 2018, and 2022), ^[10] a Cold Spring Harbor Asia Meeting (2016), ^[11] and others.

Journal of Extracellular Vesicles, Journal of Extracellular Biology, and standardization initiatives

To disseminate research in the field, the society established the peer-reviewed open access Journal of Extracellular Vesicles in 2012. ^[12] The journal was initially published by Co-Action Publishing, by Taylor & Francis from 2016-2020, and by Wiley since 2020. In addition to research and review articles, the journal periodically publishes position papers of the society that are meant to advance standardization efforts. ^{[6] [7]} In 2014, the Executive Board of Directors published a set of minimal information guidelines for publication of EV studies. ^{[13] [14]} These requirements, known as "MISEV" or "MISEV2014," mirrored similar initiatives in the fields of microarray ( MIAME) and proteomics ( MIAPE) analysis, among others. In 2017, the society's board announced its intent to update these requirements with community involvement. ^[15] The "MISEV2018" requirements were published in 2018 by Clotilde Théry and Kenneth Witwer with input from 380 co-authors. ^[16] The current consensus guidelines, known as "MISEV2023", were prepared with input from more than 1050 co-authors, using extensive crowdsourcing of expert opinion to build consensus. ^[4] The corresponding authors are Joshua Welsh, Deborah Goberdhan, Lorraine O'Driscoll, Clotilde Théry and Kenneth Witwer. ^[3]

In 2021, ISEV announced the launch of the Journal of Extracellular Biology, focusing on EVs but also other extracellular particles (EPs) and phenomena. ^{[2] [17]} The editor-in-chief is Andrew Hill.

Education

Among the educational initiatives of the society are massive open online courses (MOOCs), launched in 2016. They are available through Coursera ^{[18] [19]} and co-sponsored by the University of Gothenburg, Pohang University of Science and Technology, and the University of California, Irvine. ^[20]

References

External links

• Official website