Guidelines for diagnosing hypoprolactinemia are defined as prolactin levels below 3 µg/L in women,[3][4] and 5 µg/L in men.[12][7][8]
Management
There are few treatments which increase prolactin levels in humans. Treatment differs based on the reason for diagnosis. Women who are diagnosed with hypoprolactinemia following
lactation failure are typically advised to formula feed, although treatment with
metoclopramide has been shown to increase milk supply in clinical studies. For
subfertility, treatment may include
clomiphene citrate or
gonadotropins.[13]
^
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abGonzales GF, Velasquez G, Garcia-Hjarles M (1989). "Hypoprolactinemia as related to seminal quality and serum testosterone". Arch. Androl. 23 (3): 259–65.
doi:
10.3109/01485018908986849.
PMID2619414.
^
abUfearo CS, Orisakwe OE (September 1995). "Restoration of normal sperm characteristics in hypoprolactinemic infertile men treated with metoclopramide and exogenous human prolactin". Clin Pharmacol Ther. 58 (3): 354–9.
doi:
10.1016/0009-9236(95)90253-8.
PMID7554710.
^Corona G, Mannucci E, Jannini EA, Lotti F, Ricca V, Monami M, Boddi V, Bandini E, Balercia G, Forti G, Maggi M (May 2009). "Hypoprolactinemia: a new clinical syndrome in patients with sexual dysfunction". J. Sex. Med. 6 (5): 1457–66.
doi:
10.1111/j.1743-6109.2008.01206.x.
PMID19210705.