From Wikipedia, the free encyclopedia
Hydroxymethyl group
Hydroxymethyl group covalently bonded to an R group
Names
IUPAC name
Hydroxymethyl group
Identifiers
ChemSpider
InChI=1S/CH3O/c1-2/h2H,1H2
N Key: CBOIHMRHGLHBPB-UHFFFAOYSA-N
N
Properties
−CH2 OH
Molar mass
31.034 g·mol−1
Thermochemistry
−9 kJ/mol
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
Chemical compound
The hydroxymethyl group is the name for a
substituent with the
structural formula −CH2 −OH . It consists of a
methylene bridge (−CH2 − unit) bonded to a
hydroxyl group (−OH ). This makes the hydroxymethyl group an
alcohol . It has the identical chemical formula with the
methoxy group (−O−CH3 ) that differs only in the attachment site and orientation to the rest of the molecule. However, their
chemical properties are different.
[1]
[2]
Hydroxymethyl is the
side chain of
encoded amino acid
serine .
[3]
References
^
NAMING ORGANIC COMPOUNDS (PDF) . p. 37. Archived from
the original (PDF) on 2022-07-21. Retrieved 2022-08-08 .
^ Dong, Hao; Zheng, Erjin; Niu, Zhiyin; Zhang, Xiaoyu; Lin, Yi-Yu; Jain, Priyesh; Yu, Qiuming (2020-04-15).
"Hydroxymethyl-Functionalized PEDOT-MeOH:PSS for Perovskite Solar Cells" . ACS Applied Materials & Interfaces . 12 (15): 17571–17582.
doi :
10.1021/acsami.0c01756 .
ISSN
1944-8252 .
PMID
32204591 .
S2CID
214630308 .
Archived from the original on 2022-08-08. Retrieved 2022-08-08 .
^ Perczel, András; Farkas, Ödön; Csizmadia, Imre G. (1996-01-01).
"Peptide Models. 18. Hydroxymethyl Side-Chain Induced Backbone Conformational Shifts of l -Serine Amide. All ab Initio Conformers of For- l -Ser-NH 2" . Journal of the American Chemical Society . 118 (33): 7809–7817.
doi :
10.1021/ja960464q .
ISSN
0002-7863 .
Archived from the original on 2022-08-08. Retrieved 2022-08-08 .
External links