Pupillary hippus, also known as pupillary athetosis, is spasmodic, rhythmic, but regular dilating and contracting
pupillary movements between the
sphincter and
dilatormuscles.[1][2] Pupillary hippus comes from the Greek hippos meaning horse, perhaps due to the rhythm of the contractions representing a galloping horse.[3] Notably, hippos in antiquity referred to involuntary eye movements which are nowadays called
nystagmus.[4]
It is particularly noticeable when
pupil function is tested with a light,[2] but is independent of eye movements or changes in illumination.[1] It is usually normal, however pathological hippus can occur.[2][3]
Pathologic hippus, the phenomenon of increased oscillation or their amplitude, is associated with
aconite poisoning,[5]altered mental status, trauma, cirrhosis, and
renal disease; suggesting a common pathway of
frontal lobe dysfunction.[6] A retrospective study of 117 hospitalized patients with hippus noted an increased 30-day mortality when compared to controls and adjusted for other factors.[6]
Anisocoria - condition characterized by an unequal size of the eyes' pupils.
References
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abMcLaren J. W.; Erie J. C.; Brubaker R. F. (1992). "Computerized analysis of pupillograms in studies of alertness". Investigative Ophthalmology and Visual Science. 33: 671–6.
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abcCassin, B. and Solomon, S. Dictionary of Eye Terminology. Gainesville, Florida: Triad Publishing Company, 1990.
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abBeatty, J., & Lucero-Wagoner, B. (2000). The pupillary system. In J. T. Cacioppo, L. G. Tassinary & G. G. Bernston (Eds.), The handbook of psychophysiology (2nd ed.) (pp. 142-162). USA: Cambridge University Press.