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Biology and art professor
Helen Donis-Keller is the Michael E. Moody Professor and Professor of Biology and Art at
Olin College of Engineering in
Needham, Massachusetts .
Education and career
Donis-Keller has a B.Sc. and an H.B.Sc. from
Lakehead University . She earned her Ph.D. at
Harvard University under the direction of
Walter Gilbert in 1979.
[1] After employment at the biotechnology companies
Biogen and
Collaborative Research , she joined the faculty at
Washington University School of Medicine .
[2]
[3] In 2001, she earn an MFA in studio art from the School of the Museum of Fine Arts in Boston and Tufts University[
citation needed ] and she joined the faculty at the Olin College of Engineering.
[1] In 2012, she was named the Michael. E. Moody Faculty Chair.
[4]
Research
Donis-Keller's graduate research established a method to do RNA sequencing.
[5]
[6]
[7] During her time at Collaborative Research, her research group created the first genetic map of the human genome.
[8] Donis-Keller was unable to secure either NIH or venture funding for generating the RFLP map, but convinced Collaborative Research's management to fund the project.
[9]
[10] She continued to work on the genetic linkage map
[11] and led research into understanding the genetic basis of
cystic fibrosis ,
[12]
thyroid cancer ,
[13] and
breast cancer .
[14]
[15]
Selected publications
Donis-Keller, Helen; Maxam, Allan M.; Gilbert, Walter (1977).
"Mapping adenines, guanines, and pyrimidines in RNA" . Nucleic Acids Research . 4 (8): 2527–2538.
doi :
10.1093/nar/4.8.2527 .
ISSN
0305-1048 .
PMC
342589 .
PMID
409999 .
Doniskeller, H (October 1987).
"A genetic linkage map of the human genome" . Cell . 51 (2): 319–337.
doi :
10.1016/0092-8674(87)90158-9 .
ISSN
0092-8674 .
PMID
3664638 .
S2CID
7230640 .
Donis-Keller, Helen; Dou, Shenshen; Chi, David; Carlson, Katrin M.; Toshima, Koji; Lairmore, Terry C.; Howe, James R.; Moley, Jeffrey F.; Goodfellow, Paul; Wells, Samuel A. (1993).
"Mutations in the RET proto-oncogene are associated with MEN 2A and FMTC" . Human Molecular Genetics . 2 (7): 851–856.
doi :
10.1093/hmg/2.7.851 .
ISSN
0964-6906 .
PMID
8103403 .
Awards
Doctor of Science Degree (Honoris Causa ) from Lakehead University (1995)
[16]
Art
In addition to teaching art at Olin,
[2] Donis-Keller is herself an artist, and her art can be seen at Needham's 2021 Open Studios event
[17] and other venues.
[18]
[19]
[20] Her Ph.D. advisor, Walter Gilbert, has also begun to investigate the intersection between art and science though, in a 2015 interview, Donis-Keller did not recall his interest in art while she was a student in his lab.
[21]
References
^
a
b
"Helen Donis-Keller | Art, Science, and Education" . Retrieved 2021-09-26 .
^
a
b
"Faculty Profile for Helen Donis-Keller, Ph.D. | Olin College of Engineering" . www.olin.edu . Retrieved 2021-09-26 .
^ "Committee Biographies".
Assessing Genetic Risks: Implications for Health and Social Policy: Committee Biographies . National Academies Press (US). 1994.
^
"Olin College Names Professor Helen Donis-Keller as Inaugural Holder of the Michael E. Moody Chair" . PRWeb . December 20, 2012. Retrieved 2021-09-27 .
^ Donis-Keller, Helen; Maxam, Allan M.; Gilbert, Walter (1977).
"Mapping adenines, guanines, and pyrimidines in RNA" . Nucleic Acids Research . 4 (8): 2527–2538.
doi :
10.1093/nar/4.8.2527 .
ISSN
0305-1048 .
PMC
342589 .
PMID
409999 .
^ Donis-Keller, Helen (1979).
"Site specific enzymatic cleavage of RNA" . Nucleic Acids Research . 7 (1): 179–192.
doi :
10.1093/nar/7.1.179 .
ISSN
0305-1048 .
PMC
328004 .
PMID
386279 .
^ Donis-Keller, Helen (1980).
"Phy M: an RNase activity specific for U and A residues useful in RNA sequence analysis" . Nucleic Acids Research . 8 (14): 3133–3142.
doi :
10.1093/nar/8.14.3133 .
ISSN
0305-1048 .
PMC
324360 .
PMID
6160466 .
^ Donis-Keller, Helen; Green, Phillip; Helms, Cynthia; Cartinhour, Samuel; Weiffenback, Barbara; Stephens, Karen; Keith, Tim P.; Bowden, Donald W. (October 23, 1987).
"A Genetic Linkage Map of the Human Genome" (PDF) . Cell . 51 (2): 319–337.
doi :
10.1016/0092-8674(87)90158-9 .
PMID
3664638 .
S2CID
7230640 .
^ Cook-Deegan, Robert (1996).
The Gene Wars: Science, Politics and the Human Genome . W. W. Norton & Company.
ISBN
9780393313994 .
^ Robert Mullan Cook-Deegan; Hanna, Kathi E. (1991).
The Human Genome Project: The Formation of Federal Policies in the United States, 1986-1990 . National Academies Press (US).
^ Group, NIH/CEPH Collaborative Mapping (1992).
"A Comprehensive Genetic Linkage Map of the Human Genome" . Science . 258 (5079): 67–86.
doi :
10.1126/science.1439770 .
ISSN
0036-8075 .
JSTOR
2885812 .
^ Roberts, Leslie (1988).
"The Race for the Cystic Fibrosis Gene" . Science . 240 (4849): 141–144.
Bibcode :
1988Sci...240..141R .
doi :
10.1126/science.3281257 .
ISSN
0036-8075 .
JSTOR
1701223 .
PMID
3281257 .
^ Donis-Keller, Helen; Dou, Shenshen; Chi, David; Carlson, Katrin M.; Toshima, Koji; Lairmore, Terry C.; Howe, James R.; Moley, Jeffrey F.; Goodfellow, Paul; Wells, Samuel A. (1993).
"Mutations in the RET proto-oncogene are associated with MEN 2A and FMTC" . Human Molecular Genetics . 2 (7): 851–856.
doi :
10.1093/hmg/2.7.851 .
ISSN
0964-6906 .
PMID
8103403 .
^ Radford, Diane M.; Fair, Keri L.; Phillips, Nancy J.; Ritter, Jon H.; Steinbrueck, Todd; Holt, Matthew S.; Donis-Keller, Helen (1995-08-01).
"Allelotyping of Ductal Carcinoma in Situ of the Breast: Deletion of Loci on 8p, 13q, 16q, 17p and 17q" . Cancer Research . 55 (15): 3399–3405.
ISSN
0008-5472 .
PMID
7614479 .
^ Glass, Andrew G.; Donis-Keller, Helen; Mies, Carolyn; Russo, Jose; Zehnbauer, Barbara; Taube, Sheila; Aamodt, Roger (2001-07-01).
"The Cooperative Breast Cancer Tissue Resource: Archival Tissue for the Investigation of Tumor Markers" . Clinical Cancer Research . 7 (7): 1843–1849.
ISSN
1078-0432 .
PMID
11448894 .
^
"Past Honorary Degrees" . Lakehead University . Retrieved 2021-09-26 .
^ CULTURE, COURTESY OF NEEDHAM COUNCIL FOR ARTS AND.
"Needham students, artists showcase presentations with Storefronts Needham" . Wicked Local . Retrieved 2021-09-27 .
^
"How Genomic - Helen Donis-Keller" . www.jgsinc.org . Retrieved 2021-09-27 .
^
"Helen Donis-Keller – Krakow Witkin Gallery" . Retrieved 2021-09-27 .
^
"HELEN DONIS-KELLER, MFA 01 - Hero of the Earth, Havana - $700" . smfa.bidsquare.com . Archived from
the original on 2021-09-27. Retrieved 2021-09-27 .
^ Johnson, Carolyn Y. (March 13, 2015).
"A physicist, biologist, Nobel laureate, CEO, and now, artist - The Boston Globe" . BostonGlobe.com . Retrieved 2021-09-27 .
External links