A furanolactone is a heterocyclic chemical compound that contains both lactone and furan rings in its chemical structure.
Examples include:
- The salvinorins, [1] including the hallucinogenic compound salvinorin A
- Columbin, a bitter diterpenoid from Calumbae Radix [2] [3]
- Limonoids such as limonin, nomilin, and nomilinic acid
- Tinosporide, a diterpenoid originally isolated from Tinospora cordifolia
References
- ^ Harding WW, Schmidt M, Tidgewell K, Kannan P, Holden KG, Dersch CM, Rothman RB, Prisinzano TE (2006). "Synthetic studies of neoclerodane diterpenes from Salvia divinorum: selective modification of the furan ring". Bioorg Med Chem Lett. 16 (12): 3170–4. doi: 10.1016/j.bmcl.2006.03.062.
- ^ Kohno H, Maeda M, Tanino M, Tsukio Y, Ueda N, Wada K, Sugie S, Mori H, Tanaka T (2002). "A bitter diterpenoid furanolactone columbin from Calumbae Radix inhibits azoxymethane-induced rat colon carcinogenesis". Cancer Lett. 183 (2): 131–139. doi: 10.1016/s0304-3835(02)00159-3.
- ^ Swaminathan K, Sinha UC, Ramakumar S, Bhatt RK, Sabata BK (1989). "Structure of columbin, a diterpenoid furanolactone from Tinospora cordifolia Miers" (PDF). Acta Crystallogr C. 45 (Pt 2): 300–303. doi: 10.1107/s0108270188010583.