Functio laesa is a term used in medicine to refer to a loss of function [1] [2] or a disturbance of function. [3]
It was identified as the fifth sign of acute inflammation by Galen, who added it to the four signs identified by Celsus ( tumor, rubor, calor, and dolor). [4]
The attribution to Galen is disputed, [3] and has variously been attributed to Thomas Sydenham [5] and Rudolf Virchow. [6]