English: After initial binding of the ACE2 receptor, SARS-CoV spike is proteolytically activated and enzymatically cleaved at the S1/S2 level. S1 than dissociates from S2 and the truncated 2 subunit of the Spike protein facilitates fusion of viral and cellular membranes.
Date
Source
Rossi, G.A., Sacco, O., Mancino, E. et al. Differences and similarities between SARS-CoV and SARS-CoV-2: spike receptor-binding domain recognition and host cell infection with support of cellular serine proteases. Infection 48, 665–669 (2020).
Giovanni A. Rossi, Oliviero Sacco, Enrica Mancino, Luca Cristiani, and Fabio Midulla
This biology image could be re-created using
vector graphics as an
SVG file. This has several advantages; see
Commons:Media for cleanup for more information. If an SVG form of this image is available, please upload it and afterwards replace this template with {{
vector version available|new image name}}.
It is recommended to name the SVG file “15010 2020 1486 Fig3 HTML.svg”—then the template
Vector version available (or
Vva) does not need the new image name parameter.
to share – to copy, distribute and transmit the work
to remix – to adapt the work
Under the following conditions:
attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
https://creativecommons.org/licenses/by/4.0CC BY 4.0 Creative Commons Attribution 4.0 truetrue
Information
Captions
After initial binding of the ACE2 receptor, SARS-CoV spike is proteolytically activated and enzymatically cleaved at the S1/S2 level.
Uploaded a work by Giovanni A. Rossi, Oliviero Sacco, Enrica Mancino, Luca Cristiani, and Fabio Midulla from Rossi, G.A., Sacco, O., Mancino, E. et al. Differences and similarities between SARS-CoV and SARS-CoV-2: spike receptor-binding domain recognition and host cell infection with support of cellular serine proteases. Infection 48, 665–669 (2020). https://doi.org/10.1007/s15010-020-01486-5 with UploadWizard
File usage
The following pages on the English Wikipedia use this file (pages on other projects are not listed):