From Wikipedia, the free encyclopedia
The eggNOG database is a database of biological information hosted by the
EMBL . It is based on the original idea of COGs (clusters of orthologous groups)
[2]
[3] and expands that idea to non-supervised
orthologous groups constructed from numerous organisms.
[4] The database was created in 2007
[5] and updated to version 4.5 in 2015.
[1] eggNOG stands for e volutionary g enealogy of g enes: N on-supervised O rthologous G roups .
References
^
a
b Huerta-Cepas J, Szklarczyk D, Forslund K, Cook H, Heller D, Walter MC, Rattei T, Mende DR, Sunagawa S, Kuhn M, Jensen LJ, von Mering C, Bork P (2016).
"eggNOG 4.5: a hierarchical orthology framework with improved functional annotations for eukaryotic, prokaryotic and viral sequences" . Nucleic Acids Res . 44 (D1): D286–93.
doi :
10.1093/nar/gkv1248 .
PMC
4702882 .
PMID
26582926 .
^ Tatusov RL, Koonin EV, Lipman DJ (1997).
"A genomic perspective on protein families" . Science . 278 (5338): 631–7.
Bibcode :
1997Sci...278..631T .
doi :
10.1126/science.278.5338.631 .
PMID
9381173 .
^ Tatusov RL, Galperin MY, Natale DA, Koonin EV (2000).
"The COG database: a tool for genome-scale analysis of protein functions and evolution" . Nucleic Acids Res . 28 (1): 33–6.
doi :
10.1093/nar/28.1.33 .
PMC
102395 .
PMID
10592175 .
^ Powell, Sean; Szklarczyk, Damian; Trachana, Kalliopi; Roth, Alexander; Kuhn, Michael; Muller, Jean; Arnold, Roland; Rattei, Thomas; Letunic, Ivica; Doerks, Tobias; Jensen, Lars J; von Mering, Christian; Bork, Peer (January 2012).
"eggNOG v3.0: orthologous groups covering 1133 organisms at 41 different taxonomic ranges" . Nucleic Acids Research . 40 (D1): D284–D289.
doi :
10.1093/nar/gkr1060 .
PMC
3245133 .
PMID
22096231 .
^ Jensen LJ, Julien P, Kuhn M, von Mering C, Muller J, Doerks T, Bork P (2008).
"eggNOG: automated construction and annotation of orthologous groups of genes" . Nucleic Acids Res . 36 (Database issue): D250–4.
doi :
10.1093/nar/gkm796 .
PMC
2238944 .
PMID
17942413 .
External links