From Wikipedia, the free encyclopedia
Chemical compound
EMPA is a selective
antagonist of the
OX2 receptor, with 900-fold
selectivity in binding for OX2 over
OX1.
[1]
[2]
See also
References
-
^ Malherbe P, Borroni E, Pinard E, Wettstein JG, Knoflach F (September 2009). "Biochemical and electrophysiological characterization of almorexant, a dual orexin 1 receptor (OX1)/orexin 2 receptor (OX2) antagonist: comparison with selective OX1 and OX2 antagonists". Molecular Pharmacology. 76 (3): 618–31.
doi:
10.1124/mol.109.055152.
PMID
19542319.
S2CID
5702143.
-
^ Malherbe P, Borroni E, Gobbi L, Knust H, Nettekoven M, Pinard E, et al. (April 2009).
"Biochemical and behavioural characterization of EMPA, a novel high-affinity, selective antagonist for the OX(2) receptor". British Journal of Pharmacology. 156 (8): 1326–41.
doi:
10.1111/j.1476-5381.2009.00127.x.
PMC
2697736.
PMID
19751316.