Company type | Private |
---|---|
Industry | |
Founded | 2019 |
Headquarters | Boston, Massachusetts |
Key people | Mark Rus ( Chief Executive Officer) |
Website |
delixtherapeutics |
Delix Therapeutics is an American biotech company based in Boston, Massachusetts. [1] The company develops novel neuroplasticity-promoting therapeutics for central nervous system (CNS) diseases such as depression and post-traumatic stress disorder (PTSD). [2] It was co-founded in 2019 by David E. Olson and Nick Haft. [3]
The company was founded to develop novel, non-hallucinogenic psychoplastogens, also known as neuroplastogens, to better treat mental health disorders at scale. David E. Olson founded the company following his discovery that psychedelics are highly potent neuroplasticity-promoting compounds. [2] In September 2021, Delix secured a Series A financing round, the largest in the space, to continue their work focused on neuroplastogens and neuroplasticity therapeutics. [4] Also in Fall of 2021, Delix joined the National Institute on Drug Abuse industry partnering program to screen psychoplastogens in models of substance use disorder. [2] In 2021, the company expanded the leadership team, adding a new CEO, [5] CSO, [1] and CMO [1]
In 2021, Delix was named one of the Fierce 15 of Biotech. [6] In 2022, Nature named Delix Spinout of the Year [7] and Delix was awarded the Healthcare Businesswomen's Association (HBA) ACE award. [8] In 2023, Delix was a finalist for the Prix Galien award for Best Startup [9] and the BWB award for Biotech Innovation of the Year [10] and won the Biotech Breakthrough Award for Neuroscience Therapeutics Company of the Year. [11]
To date, the company has synthesized over 2000 novel psychoplastogens. [12] Many of these small molecule compounds are analogs of known psychedelics such as ibogaine and 5-MeO-DMT. [13] Delix focuses on the development of non-hallucinogenic psychoplastogens as scalable alternatives to first-generation hallucinogenic psychoplastogens like ketamine and psilocybin. [14] Their compounds have been engineered to lack cardiotoxicity and psychostimulant properties characteristic of other first-generation psychoplastogens. [15] Two of the company’s known scaffolds are tabernanthalog and AAZ-A-154. [16] Delix has licensed these compounds from UC Davis. [17]
{{
cite web}}
: CS1 maint: numeric names: authors list (
link)