From Wikipedia, the free encyclopedia
Medical condition
Cornea verticillata Other names Fleischer vortex
[1]
Cornea verticillata: A bilateral, whorl-like corneal pattern of cream colored lines in a patient with Fabry disease.
Specialty Ophthalmology Treatment Discontinuation of the offending drug results in complete resolution of the opacity.
Cornea verticillata , also called vortex keratopathy or whorl keratopathy , is a condition characterised by
corneal deposits at the level of the
basal epithelium forming a faint golden-brown whorl pattern.
[2] It is seen in
Fabry disease or in case of prolonged
amiodarone intake.
[3] Furthermore, it is a common adverse side effect of the use of
rho-kinase inhibitors in
glaucoma therapy .
[4]
Presentation
No ocular complaints or visual difficulty is usually present.
[3]
[5]
Pathophysiology
This keratopathy is probably a type of drug-induced lipidosis.
[3]
Diagnosis
This section is empty. You can help by
adding to it .
(September 2022 )
References
^
"Definition: 'Cornea Verticillata' " . MediLexicon. Retrieved 29 November 2013 .
^ van der Tol, Linda; Sminia, Marije L; Hollak, Carla E M; Biegstraaten, Marieke (2016).
"Cornea verticillata supports a diagnosis of Fabry disease in non-classical phenotypes: results from the Dutch cohort and a systematic review" . British Journal of Ophthalmology . 100 (1): 3–8.
doi :
10.1136/bjophthalmol-2014-306433 .
ISSN
0007-1161 .
PMID
25677671 .
^
a
b
c Chew, E; Ghosh, M; McCulloch, C (June 1982). "Amiodarone-induced cornea verticillata". Canadian Journal of Ophthalmology . 17 (3): 96–9.
PMID
7116220 .
^ Rivera, Sean S.; Radunzel, Nicole; Boese, Erin A. (2023-11-01).
"Symptomatic Netarsudil-Induced Verticillata" . JAMA Ophthalmology . 141 (11): e232949.
doi :
10.1001/jamaophthalmol.2023.2949 .
ISSN
2168-6173 .
PMID
37971506 .
S2CID
265267017 .
^ Graff, Jordan M. (February 21, 2005).
"Verticillata" . University of Iowa Health Care, Ophthalmology and Visual Sciences. Retrieved 29 November 2013 .