Names | |
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IUPAC name
8α-Cedran-8β-ol
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Systematic IUPAC name
(3R,3aS,6R,7R,8aS)-3,6,8,8-Tetramethyloctahydro-1H-3a,7-methanoazulen-6-ol | |
Identifiers | |
3D model (
JSmol)
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ChEMBL | |
ChemSpider | |
ECHA InfoCard | 100.000.942 |
PubChem
CID
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UNII | |
CompTox Dashboard (
EPA)
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Properties | |
C15H26O | |
Molar mass | 222.372 g·mol−1 |
Density | 1.01 g/mL |
Melting point | 86 to 87 °C (187 to 189 °F; 359 to 360 K) [1] |
Boiling point | 273 °C (523 °F; 546 K) [2] |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
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Cedrol is a sesquiterpene alcohol found in the essential oil of conifers ( cedar oil), especially in the genera Cupressus (cypress) and Juniperus (juniper). It has also been identified in Origanum onites, a plant related to oregano. [3] Its main uses are in the chemistry of aroma compounds. [4] It makes up about 19% of cedarwood oil Texas and 15.8% of cedarwood oil Virginia. [5]
Cedrol has not been proven to be toxic in humans. It has been shown to have antioxidant and antiinflammatory along with other beneficial effects. In skin sensitization tests 2/20 people showed negative effects, and on the second test there was no sensitivity found. This compound and ones similar have been found to have antiseptic, anti-inflammatory, antispasmodic, tonic, astringent, diuretic, sedative, insecticidal, and antifungal activities in vitro. [6] These compounds are used globally in traditional medicine and cosmetics. [7] Results of a 2015 study suggest that cedrol strongly attracts pregnant female mosquitoes after they have fed, which can be used to create cedrol-baited traps. [8]