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Articles relating to the Paleo-Indians, the first peoples who entered, and subsequently inhabited, the Americas during the final glacial episodes of the late Pleistocene period. The term "Paleo-Indians" applies specifically to the lithic period in the Western Hemisphere and is distinct from the term " Paleolithic".

The population of the era consisted of small isolated groups of hunter-gatherers, who are thought to have crossed the Bering Strait from North Asia. It is likely that there were multiple such crossings between 45,000 to 12,000 BCE.