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Farmitalia
Industry
Pharmaceutical
Founded
1935
Farmitalia was an Italian pharmaceutical company best known for its parallel discovery with
Rhone-Poulenc of
daunorubicin and subsequent discovery of
doxorubicin.[1]
Farmitalia had been founded in 1935 as a joint venture by Rhone-Poulenc and
Montecatini.[2] Farmitalia occupied a position of choice in the world rankings of the profession, not only in Italy, but also at the world level with in particular the patent of Adriamycin, an anti-cancer drug qualified. From its creation, Farmaceutici Italia buys the Schiapparelli factory.[3]
In 1978, Farmitalia was merged with Carlo Erba SpA, an Italian pharmaceutical company that had been founded in 1853 by the pharmacist
Carlo Erba [
it], in which Montecatini had acquired a controlling interest in 1971. The merged company was called Farmitalia Carlo Erba SpA.[2]
Farmitalia Carlo Erba was acquired by
Pharmacia in 1993,[4] then Pharmacia was acquired by
Pfizer in 2003.[5]
Drugs discovered at Farmitalia that reached the market included (with date of first publication):
^Baruffa, G (1966). "Clinical trials in Plasmodium falciparum malaria with a long-acting sulphonamide". Trans R Soc Trop Med Hyg. 60 (2): 222–4.
doi:
10.1016/0035-9203(66)90030-7.
PMID5332105.
^Per prior citation, the first publication: Camerino, B; Palamidessi, G (1960). "Derivati della parazina II. Sulfonamdopir (in Italian)". Gazz Chim Ital. 90: 1802–1815.
^Grein A, et al. Descrizione e classificazione di un attinomicete (Streptonryces peucetius sp. nova) produttore di una sostanza ad attivita antitumorale. Giorn. Microbiol. 11: 109~ 118, 1963
^Arcamone F, Cassinelli G, Fantini G, et al. (1969). "Adriamycin, 14-hydroxydaunomycin, a new antitumor antibiotic from S. peucetius var. caesius". Biotechnol Bioeng. 11 (6): 1101–10.
doi:
10.1002/bit.260110607.
PMID5365804.
S2CID21897153.
^Cocchiara, G; et al. (1991). "Comparison of the disposition and of the metabolic pattern of Reboxetine, a new antidepressant, in the rat, dog, monkey and man". Eur J Drug Metab Pharmacokinet. 16 (3): 231–9.
doi:
10.1007/bf03189965.
PMID1814741.
S2CID874781.
^First publication per prior citation: Melloni, M; et al. (1984). "Potential antidepressant agents. α-aryloxy-benzyl derivatives of ethanolamine and morpholine". Eur J Med Chem. 3: 235–242.