From Wikipedia, the free encyclopedia
Allergen produced by dogs
Can f 1 or canis familiaris allergen 1 is a
lipocalin
[1]
allergen produced by dogs
[2] in their tongue epithelial tissue.
[3] It is homologous with the human lipocalin
LCN1 .
[4]
[5]
References
^
Major allergen Can f 1 UniProtKB .
^ Grammer, Leslie C. and Paul A. Greenberger (2009),
Patterson's Allergic Diseases p. 97.
^ Konieczny, A; Morgenstern, J P; Bizinkauskas, C B; Lilley, C H; Brauer, A W; Bond, J F; Aalberse, R C; Wallner, B P; Kasaian, M T (December 1997).
"The major dog allergens, Can f 1 and Can f 2, are salivary lipocalin proteins: cloning and immunological characterization of the recombinant forms" . Immunology . 92 (4): 577–586.
doi :
10.1046/j.1365-2567.1997.00386.x .
ISSN
0019-2805 .
PMC
1364166 .
PMID
9497502 .
^ Jensen-Jarolim, E.; Pacios, L.F.; Bianchini, R.; Hofstetter, G.; Roth-Walter, F. (March 2016).
"Structural similarities of human and mammalian lipocalins, and their function in innate immunity and allergy" . Allergy . 71 (3): 286–294.
doi :
10.1111/all.12797 .
ISSN
0105-4538 .
PMC
4949658 .
PMID
26497994 .
^ Breitenbuecher, Christina; Belanger, Janelle M.; Levy, Kerinne; Mundell, Paul; Fates, Valerie; Gershony, Liza; Famula, Thomas R.; Oberbauer, Anita M. (2016-04-22).
"Protein expression and genetic variability of canine Can f 1 in golden and Labrador retriever service dogs" . Canine Genetics and Epidemiology . 3 : 3.
doi :
10.1186/s40575-016-0031-3 .
ISSN
2052-6687 .
PMC
4840867 .
PMID
27110374 .