Big Creek is a stream in Iron and Wayne counties of the U.S. state of Missouri. [1] It is a tributary of the St. Francis River. [2] The stream headwaters are at 37°33′45″N 90°40′34″W / 37.56250°N 90.67611°W in Iron County and the confluence with the St. Francis is at 37°14′09″N 90°30′25″W / 37.23583°N 90.50694°W in northern Wayne County. [1]
Big Creek was so named on account of its relatively large size. [3]
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