Indian multinational biotechnology company and vaccine manufacturer
17°39′55″N 78°36′17″E / 17.6652°N 78.6047°E / 17.6652; 78.6047
Bharat Biotech International Limited (BBIL) is an Indian multinational
biotechnology company based in
Hyderabad , which is engaged in
drug discovery ,
drug development , and the manufacture of
vaccines ,
biotherapeutics ,
pharmaceuticals and healthcare products.
[5]
Overview
Bharat Biotech has its manufacturing facility situated at
Genome Valley ,
Hyderabad , India.
[5] As of July 2020, the company has over 700 employees
[6] and has a presence worldwide.
[5]
The company has been responsible for developing an eco-friendly recombinant
[7] and a naturally attenuated strain derived Rotavirus vaccine called ROTAVAC.
[8]
[9] They were one of the first to develop vaccines for viral diseases like
Chikungunya
[10]
[11] and
Zika .
[12]
[13] The company also produces vaccines for
Japanese Encephalitis .
[14] Bharat Biotech has
biosafety level 3 (BSL3) laboratories.
[15]
COVID-19 vaccine development
In April 2020, the company announced that they have partnered with US-based company FluGen and
University of Wisconsin-Madison to develop a COVID-19 vaccine.
[16]
[17]
A 5ml vial of Covaxin
In May 2020, Indian Council of Medical Research's (
ICMR 's)
National Institute of Virology approved and provided the virus strains for developing a fully indigenous
COVID-19 vaccine.
[18]
[19] On June 29, 2020, the company got permission to conduct Phase 1 and Phase 2
clinical trials in India for a developmental
COVID-19 vaccine named
Covaxin , from the Drugs Controller General of India (
DCGI ),
Government of India .
[20]
[21]
[22]
[23] The Central Drugs Laboratory (CDL) at Kasauli in Himachal Pradesh has been engaged in testing experimental batches of Bharat Biotech's COVID-19 vaccine Covaxin on a priority basis.
[24] A total of 12 sites were selected by the
Indian Council for Medical Research for Phase I and II randomised, double-blind and placebo-controlled clinical trials of vaccine candidate.
[25]
[26]
In September 2020, the company announced that it was going to manufacture the novel chimp-adenovirus , a single dose
intranasal vaccine (codenamed
BBV154 ) for
COVID-19 being developed in collaboration with the American company Precision virologics
[27] and
Washington University School of Medicine in
St. Louis, Missouri . It is currently undergoing clinical trials.
[28]
[29] On October 12 2021, Bharat Biotech's Covaxin got approved for usage on children between 2 and 18 years of age.
[30]
Attempted data theft
In March 2021,
Reuters reported that Chinese state-backed cyber-espionage group
Red Apollo targeted Bharat Biotech's intellectual property for
exfiltration .
[31]
See also
References
^
"WHO prequalifies new rotavirus vaccine" . WHO . Archived from
the original on 17 July 2020. Retrieved 2 July 2020 .
^
"WHO recommends use of first typhoid conjugate vaccine" . WHO . Archived from
the original on 7 September 2018. Retrieved 2 July 2020 .
^
a
b
"Bharat Biotech International Limited: Ratings reaffirmed" . ICRA . Retrieved 16 April 2024 .
^
"Bharat Biotech buys Chiron Behring Vaccines from GSK" . The Hindu BusinessLine . 15 February 2019.
Archived from the original on 31 August 2020. Retrieved 1 July 2020 .
^
a
b
c
"Bharat Biotech International Ltd" . www.bloomberg.com .
Archived from the original on 16 November 2020. Retrieved 3 July 2020 .
^
"Leading Biotech Vaccine Manufacturers in India - Bharat Biotech" . www.bharatbiotech.com .
Archived from the original on 5 July 2020. Retrieved 30 June 2020 .
^
"Process for the preparation and purification of recombinant proteins" . patents.google.com . US patent No US8956812B2. 23 August 2004.
Archived from the original on 9 May 2021. Retrieved 30 June 2020 .
^ Bhandari, Nita; Rongsen-Chandola, Temsunaro; Bavdekar, Ashish; John, Jacob; Antony, Kalpana; Taneja, Sunita; Goyal, Nidhi; Kawade, Anand; Kang, Gagandeep; Rathore, Sudeep Singh; Juvekar, Sanjay; Muliyil, Jayaprakash; Arya, Alok; Shaikh, Hanif; Abraham, Vinod; Vrati, Sudhanshu; Proschan, Michael; Kohberger, Robert; Thiry, Georges; Glass, Roger; Greenberg, Harry B; Curlin, George; Mohan, Krishna; Harshavardhan, G V J A; Prasad, Sai; Rao, T S; Boslego, John; Bhan, Maharaj Kishan (June 2014).
"Efficacy of a monovalent human-bovine (116E) rotavirus vaccine in Indian infants: a randomised, double-blind, placebo-controlled trial" . The Lancet . 383 (9935): 2136–2143.
doi :
10.1016/S0140-6736(13)62630-6 .
PMC
4532697 .
PMID
24629994 .
^ Kang, G (October 2006).
"Rotavirus vaccines" . Indian Journal of Medical Microbiology . 24 (4): 252–7.
doi :
10.1016/S0255-0857(21)02284-2 .
PMC
2481304 .
PMID
17185842 .
^
"Bharat Biotech's Zika, Chikungunya vaccines to enter Phase II trials; focus now on private label market" . Moneycontrol .
Archived from the original on 30 June 2020. Retrieved 30 June 2020 .
^
"CEPI, 치쿤구니아 백신 개발 위해 국제백신연구소-바라트 바이오텍 컨소시엄에 최대 1410만달러 지원" . CEPI, 치쿤구니아 백신 개발 위해 국제백신연구소-바라트 바이오텍 컨소시엄에 최대 1410만달러 지원 - 뉴스와이어 (in Korean). 3 June 2020.
^
"Bharat Biotech gets breakthrough in developing Zika vaccine" . The Economic Times . 4 February 2016.
Archived from the original on 9 May 2021. Retrieved 30 June 2020 .
^
"CEPI awards up to US$14.1million to consortium of IVI and Bharat Biotech to advance development of Chikungunya vaccine in collaboration with Ind-CEPI – IVI" . www.ivi.int . International Vaccine Institute. 3 June 2020.
Archived from the original on 24 September 2020. Retrieved 30 June 2020 .
^ Singh, Anit; Mitra, Monjori; Sampath, Gadey; Venugopal, P.; Rao, J. Venkateswara; Krishnamurthy, B.; Gupta, Mukesh Kumar; Sri Krishna, S.; Sudhakar, B.; Rao, N. Bhuvaneswara; Kaushik, Yashpal; Gopinathan, K.; Hegde, Nagendra R.; Gore, Milind M.; Krishna Mohan, V.; Ella, Krishna M. (1 September 2015).
"A Japanese Encephalitis Vaccine From India Induces Durable and Cross-protective Immunity Against Temporally and Spatially Wide-ranging Global Field Strains" . Journal of Infectious Diseases . 212 (5): 715–725.
doi :
10.1093/infdis/jiv023 .
PMID
25601942 .
^
"Slow off the starting blocks for Bharat Biotech's Covaxin mass production" . The New Indian Express . 17 May 2021. Retrieved 4 June 2021 .
^
"UW-Madison, Flugen, Bharat Biotech to develop coroflu, a coronavirus vaccine" . Global Health Institute .
Archived from the original on 10 February 2021. Retrieved 30 June 2020 .
^
"Bharat Biotech ties up with US varsity for Covid vaccine" . Hindustan Times . 20 May 2020.
Archived from the original on 3 May 2021. Retrieved 30 June 2020 .
^
"ICMR teams up with Bharat Biotech to develop Covid-19 vaccine" . Livemint . 9 May 2020.
Archived from the original on 3 May 2021. Retrieved 30 June 2020 .
^ Chakrabarti, Angana (10 May 2020).
"India to develop 'fully indigenous' Covid vaccine as ICMR partners with Bharat Biotech" . ThePrint .
Archived from the original on 3 May 2021. Retrieved 30 June 2020 .
^
"India's First COVID-19 Vaccine Candidate Approved for Human Trials" . The New York Times . 29 June 2020.
Archived from the original on 2 July 2020. Retrieved 30 June 2020 .
^
"Human trial of India coronavirus vaccine announced" . BBC News . 30 June 2020.
Archived from the original on 3 May 2021. Retrieved 30 June 2020 .
^
"Bharat Biotech's Covid vaccine 1st in India to get approval for human trials" . The Indian Express . 30 June 2020.
Archived from the original on 3 May 2021. Retrieved 30 June 2020 .
^
"Covaxin: India's first COVID19 vaccine candidate from Bharat Biotech to begin human trials; check details" . The Financial Express . 30 June 2020.
Archived from the original on 3 May 2021. Retrieved 30 June 2020 .
^
"Bharat Biotech COVID-19 vaccine: Testing underway at CDL-Kasauli, volunteer enrolment begins" . Moneycontrol .
Archived from the original on 10 July 2020. Retrieved 10 July 2020 .
^
"Human clinical trials of potential Covid-19 vaccine 'COVAXIN' started at AIIMS" . DD News . Prasar Bharati, Ministry of I & B, Government of India. 25 July 2020.
Archived from the original on 24 January 2021. Retrieved 7 August 2020 .
^
"Delhi: 30-year-old is first to get dose of trial drug Covaxin" . The Indian Express . 25 July 2020.
Archived from the original on 16 March 2021. Retrieved 7 August 2020 .
^
"COVID-19 | Office of Technology Management/Tech Transfer | Washington University in St. Louis" .
^
"Bharat Biotech to make a billion doses of an intranasal adenovirus vaccine" . The Indian Express . 23 September 2020.
Archived from the original on 3 May 2021. Retrieved 23 September 2020 .
^
"Bharat Biotech Partners With US University For Covid Intranasal Vaccine" . NDTV.com .
Archived from the original on 3 May 2021. Retrieved 23 September 2020 .
^
"COVID-19: Covaxin Vaccine Approved For Children Between 2 to 18" . The Live Mirror . 12 October 2021. Retrieved 12 October 2021 .
^ Das, Krishna N. (1 March 2021).
"Chinese hackers target Indian vaccine makers SII, Bharat Biotech, says security firm" .
Reuters .
Archived from the original on 3 May 2021. Retrieved 1 March 2021 .
External links