From Wikipedia, the free encyclopedia
Befloxatone
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Names
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Preferred IUPAC name
(5R)-5-(Methoxymethyl)-3-{4-[(3R)-4,4,4-trifluoro-3-hydroxybutoxy]phenyl}-1,3-oxazolidin-2-one
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Identifiers
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ChEMBL
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ChemSpider
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KEGG
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UNII
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InChI=1S/C15H18F3NO5/c1-22-9-12-8-19(14(21)24-12)10-2-4-11(5-3-10)23-7-6-13(20)15(16,17)18/h2-5,12-13,20H,6-9H2,1H3/t12-,13-/m1/s1 YKey: IALVDLPLCLFBCF-CHWSQXEVSA-N YInChI=1/C15H18F3NO5/c1-22-9-12-8-19(14(21)24-12)10-2-4-11(5-3-10)23-7-6-13(20)15(16,17)18/h2-5,12-13,20H,6-9H2,1H3/t12-,13-/m1/s1 Key: IALVDLPLCLFBCF-CHWSQXEVBB
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O=C2O[C@H](CN2c1ccc(OCC[C@@H](O)C(F)(F)F)cc1)COC
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Properties
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C15H18F3NO5
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Molar mass
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349.30233
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Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
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Chemical compound
Befloxatone (MD-370,503) is a
reversible inhibitor of monoamine oxidase A.
[1]
[2]
References
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^ Emilien, G (March 1999). "Befloxatone (Synthelabo)". IDrugs. 2 (3): 247–253.
PMID
16160936.
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^ Warot, Dominique; Berlin, Ivan; Patat, Alain; Durrieu, Geneviève; Zieleniuk, Isabelle; Puech, Alain J (October 1996). "Effects of Befloxatone, a Reversible Selective Monoamine Oxidase-A Inhibitor, on Psychomotor Function and Memory in Healthy Subjects". The Journal of Clinical Pharmacology. 1552-4604. 36 (10): 942–950.
doi:
10.1002/j.1552-4604.1996.tb04762.x.
PMID
8930782.
S2CID
36177710.