Mutations in the fibrillin-2 gene, in chromosome 5q23
Arachnodactyly ("spider fingers") is a medical condition that is characterized by fingers and toes that are abnormally long and slender, in comparison to the palm of the hand and arch of the foot. In some cases, the thumbs of an individual with the condition are pulled inwards towards the palm. This condition is present at birth.
It remains unconfirmed whether composer
Sergei Rachmaninoff's abnormally large reach on a piano was a result of arachnodactyly due to
Marfan syndrome, as the pianist exhibited no other signs of the disease.[6]
It is also uncertain if blues guitarist and vocalist
Robert Johnson's long fingers were due to Marfan syndrome.[citation needed]