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| Other names | Rhabarberone |
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Routes of administration | Oral |
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| ECHA InfoCard | 100.006.884 |
| Chemical and physical data | |
| Formula | C15H10O5 |
| Molar mass | 270.240 g·mol−1 |
| 3D model ( JSmol) | |
| Melting point | 223 to 224 °C (433 to 435 °F) Sublimes in CO2 stream |
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Aloe emodin (1,8-dihydroxy-3-(hydroxymethyl)anthraquinone) is an anthraquinone and an isomer of emodin present in aloe latex, an exudate from the aloe plant. It has a strong stimulant-laxative action. [1] Aloe emodin is not carcinogenic when applied to the skin, although it may increase the carcinogenicity of some kinds of radiation. [2] [3]
Aloe emodin is found in the gel, sap or leaves of aloe vera, the socotrine aloe, Barbados aloe, and Zanzibar aloes, the bark of Frangula ( Rhamnus frangula) and cascara sagrada ( Rhamnus purshiana), the leaves of Senna ( Cassia angustifolia), and the rhizome of rhubarb ( Rheum rhaponticum).[ citation needed] Aloe-emodin has not been found in Natal aloes.[ citation needed]
References
- ^ The Merck Index (12th ed.). p. 313.
- ^ Badgwell DB, Walker CM, Baker WT, Strickland FM (March 2004). "Ethanol and aloe emodin alter the p53 mutational spectrum in ultraviolet radiation-induced murine skin tumors". Molecular Carcinogenesis. 39 (3): 127–38. doi: 10.1002/mc.10170. PMID 14991742. S2CID 24146785.
- ^ National Toxicology Program (September 2010). "Photocarcinogenesis study of aloe vera [CAS NO. 481-72-1(Aloe-emodin)] in SKH-1 mice (simulated solar light and topical application study)". National Toxicology Program Technical Report Series (553): 7–33, 35–97, 99-103 passim. PMID 21031007.