From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
For other uses, see
Parva .
Alpha-parvin is a
protein that in humans is encoded by the PARVA
gene .
[5]
[6]
Members of the parvin family, including PARVA,
PARVB and
PARVG , are actin-binding proteins associated with focal contacts.[supplied by OMIM]
[6]
References
Further reading
Nikolopoulos SN, Turner CE (2001).
"Actopaxin, a new focal adhesion protein that binds paxillin LD motifs and actin and regulates cell adhesion" . J. Cell Biol . 151 (7): 1435–48.
doi :
10.1083/jcb.151.7.1435 .
PMC
2150668 .
PMID
11134073 .
Tu Y, Huang Y, Zhang Y, et al. (2001).
"A new focal adhesion protein that interacts with integrin-linked kinase and regulates cell adhesion and spreading" . J. Cell Biol . 153 (3): 585–98.
doi :
10.1083/jcb.153.3.585 .
PMC
2190577 .
PMID
11331308 .
Nikolopoulos SN, Turner CE (2002).
"Molecular dissection of actopaxin-integrin-linked kinase-Paxillin interactions and their role in subcellular localization" . J. Biol. Chem . 277 (2): 1568–75.
doi :
10.1074/jbc.M108612200 .
PMID
11694518 .
Korenbaum E, Olski TM, Noegel AA (2002). "Genomic organization and expression profile of the parvin family of focal adhesion proteins in mice and humans". Gene . 279 (1): 69–79.
doi :
10.1016/S0378-1119(01)00743-0 .
PMID
11722847 .
Zhang Y, Chen K, Tu Y, et al. (2003). "Assembly of the PINCH-ILK-CH-ILKBP complex precedes and is essential for localization of each component to cell-matrix adhesion sites". J. Cell Sci . 115 (Pt 24): 4777–86.
doi :
10.1242/jcs.00166 .
PMID
12432066 .
S2CID
13630628 .
Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903.
Bibcode :
2002PNAS...9916899M .
doi :
10.1073/pnas.242603899 .
PMC
139241 .
PMID
12477932 .
Ota T, Suzuki Y, Nishikawa T, et al. (2004).
"Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40–5.
doi :
10.1038/ng1285 .
PMID
14702039 .
Aboulaich N, Vainonen JP, Strålfors P, Vener AV (2005).
"Vectorial proteomics reveal targeting, phosphorylation and specific fragmentation of polymerase I and transcript release factor (PTRF) at the surface of caveolae in human adipocytes" . Biochem. J . 383 (Pt 2): 237–48.
doi :
10.1042/BJ20040647 .
PMC
1134064 .
PMID
15242332 .
Zhang Y, Chen K, Tu Y, Wu C (2004).
"Distinct roles of two structurally closely related focal adhesion proteins, alpha-parvins and beta-parvins, in regulation of cell morphology and survival" . J. Biol. Chem . 279 (40): 41695–705.
doi :
10.1074/jbc.M401563200 .
PMID
15284246 .
Clarke DM, Brown MC, LaLonde DP, Turner CE (2004).
"Phosphorylation of actopaxin regulates cell spreading and migration" . J. Cell Biol . 166 (6): 901–12.
doi :
10.1083/jcb.200404024 .
PMC
2172128 .
PMID
15353548 .
Gerhard DS, Wagner L, Feingold EA, et al. (2004).
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7.
doi :
10.1101/gr.2596504 .
PMC
528928 .
PMID
15489334 .
LaLonde DP, Brown MC, Bouverat BP, Turner CE (2005).
"Actopaxin interacts with TESK1 to regulate cell spreading on fibronectin" . J. Biol. Chem . 280 (22): 21680–8.
doi :
10.1074/jbc.M500752200 .
PMID
15817463 .
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature . 437 (7062): 1173–8.
Bibcode :
2005Natur.437.1173R .
doi :
10.1038/nature04209 .
PMID
16189514 .
S2CID
4427026 .
Ewing RM, Chu P, Elisma F, et al. (2007).
"Large-scale mapping of human protein-protein interactions by mass spectrometry" . Mol. Syst. Biol . 3 (1): 89.
doi :
10.1038/msb4100134 .
PMC
1847948 .
PMID
17353931 .