From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
Apoptotic chromatin condensation inducer in the nucleus is a
protein that in
humans is encoded by the ACIN1
gene .
[5]
[6]
[7]
References
^
a
b
c
GRCh38: Ensembl release 89: ENSG00000100813 –
Ensembl , May 2017
^
a
b
c
GRCm38: Ensembl release 89: ENSMUSG00000022185 –
Ensembl , May 2017
^
"Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^
"Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ Ishikawa K, Nagase T, Suyama M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Dec 1998).
"Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro" . DNA Res . 5 (3): 169–76.
doi :
10.1093/dnares/5.3.169 .
PMID
9734811 .
^ Sahara S, Aoto M, Eguchi Y, Imamoto N, Yoneda Y, Tsujimoto Y (Sep 1999). "Acinus is a caspase-3-activated protein required for apoptotic chromatin condensation". Nature . 401 (6749): 168–73.
Bibcode :
1999Natur.401..168S .
doi :
10.1038/43678 .
PMID
10490026 .
S2CID
4364282 .
^
"Entrez Gene: ACIN1 apoptotic chromatin condensation inducer 1" .
External links
Further reading
Zermati Y, Garrido C, Amsellem S, et al. (2001).
"Caspase activation is required for terminal erythroid differentiation" . J. Exp. Med . 193 (2): 247–54.
doi :
10.1084/jem.193.2.247 .
PMC
2193347 .
PMID
11208865 .
Sordet O, Rébé C, Plenchette S, et al. (2003).
"Specific involvement of caspases in the differentiation of monocytes into macrophages" . Blood . 100 (13): 4446–53.
doi :
10.1182/blood-2002-06-1778 .
PMID
12393560 .
Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903.
Bibcode :
2002PNAS...9916899M .
doi :
10.1073/pnas.242603899 .
PMC
139241 .
PMID
12477932 .
Shu H, Chen S, Bi Q, et al. (2004).
"Identification of phosphoproteins and their phosphorylation sites in the WEHI-231 B lymphoma cell line" . Mol. Cell. Proteomics . 3 (3): 279–86.
doi :
10.1074/mcp.D300003-MCP200 .
PMID
14729942 .
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004).
"Large-scale characterization of HeLa cell nuclear phosphoproteins" . Proc. Natl. Acad. Sci. U.S.A . 101 (33): 12130–5.
Bibcode :
2004PNAS..10112130B .
doi :
10.1073/pnas.0404720101 .
PMC
514446 .
PMID
15302935 .
Jin J, Smith FD, Stark C, et al. (2004).
"Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization" . Curr. Biol . 14 (16): 1436–50.
Bibcode :
2004CBio...14.1436J .
doi :
10.1016/j.cub.2004.07.051 .
PMID
15324660 .
S2CID
2371325 .
Kim JE, Tannenbaum SR, White FM (2005). "Global phosphoproteome of HT-29 human colon adenocarcinoma cells". J. Proteome Res . 4 (4): 1339–46.
doi :
10.1021/pr050048h .
PMID
16083285 .
Hu Y, Yao J, Liu Z, et al. (2005).
"Akt phosphorylates acinus and inhibits its proteolytic cleavage, preventing chromatin condensation" . EMBO J . 24 (20): 3543–54.
doi :
10.1038/sj.emboj.7600823 .
PMC
1276706 .
PMID
16177823 .
Joselin AP, Schulze-Osthoff K, Schwerk C (2006).
"Loss of Acinus inhibits oligonucleosomal DNA fragmentation but not chromatin condensation during apoptosis" . J. Biol. Chem . 281 (18): 12475–84.
doi :
10.1074/jbc.M509859200 .
PMID
16537548 .
Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol . 24 (10): 1285–92.
doi :
10.1038/nbt1240 .
PMID
16964243 .
S2CID
14294292 .
Olsen JV, Blagoev B, Gnad F, et al. (2006).
"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks" . Cell . 127 (3): 635–48.
doi :
10.1016/j.cell.2006.09.026 .
PMID
17081983 .
Shu Y, Iijima T, Sun W, et al. (2007). "The ACIN1 gene is hypermethylated in early stage lung adenocarcinoma". Journal of Thoracic Oncology . 1 (2): 160–7.
doi :
10.1097/01243894-200602000-00010 .
PMID
17409846 .