Pablo Carreño Busta defeated
Jaume Munar in the final, 6–1, 2–6, 6–4 to win the inaugural Men's Singles tennis title at the 2021 Andalucía Open. Notably, this was the first tournament in ATP history to feature 4 semifinalists from the same nation.
This was the first edition of the tournament, primarily organised due to the cancellation of some tournaments in 2021, due to the
COVID-19 pandemic.[1]
Seeds
The top four
seeds received a
bye into the second round.