1st Duke of Buckingham may refer to:

• George Villiers, 1st Duke of Buckingham (1592–1628), favourite of King James I of England
• Humphrey Stafford, 1st Duke of Buckingham (1402–1460), English nobleman
• John Sheffield, 1st Duke of Buckingham and Normanby (1647–1721), English poet
• Richard Temple-Grenville, 1st Duke of Buckingham and Chandos (1776–1839), Knight of the Garter

This disambiguation page lists articles associated with the title 1st Duke of Buckingham.
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