The first leg was held on 8 September 1965 at
San Siro, home of Inter, who won the match 3–0, with goals from
Joaquín Peiró and
Sandro Mazzola.
La Doble Visera hosted the return leg 7 days later on 15 September 1965, and ended in a goalless draw. Inter thus won the Intercontinental Cup for the second year in a row.