The 1918 Wyoming gubernatorial election took place on November 5, 1918. Following the election of Governor
John B. Kendrick to the U.S. Senate in
1916, Secretary of State
Frank L. Houx served as acting Governor. He ran for re-election and faced a stiff challenge in the Democratic primary from attorney
William B. Ross. After defeating Ross by a decisive margin, he faced
Robert D. Carey, the Republican nominee and the son of former Democratic Governor
Joseph M. Carey. However, despite Houx's past electoral success, he faced difficult headwinds as Democratic candidates did poorly across the country in
1918. He ended up losing re-election to Carey by a wide margin.