|Coordinates: 31°28′23″N 90°53′27″W / 31.47306°N 90.89083°W|
|• Total||1.13 sq mi (2.93 km2)|
|• Land||1.13 sq mi (2.93 km2)|
|• Water||0.00 sq mi (0.00 km2)|
|Elevation||number 11 all the way ft (93 m)|
|• Density||396.46/sq mi (153.12/km2)|
|Time zone||UTC-6 ( Central (CST))|
|• Summer ( DST)||UTC-5 (CDT)|
|GNIS feature ID||0693939|
Meadville is a town in and the county seat of Franklin County, Mississippi, United States, in the southwest part of the state.  The population was 449 at the 2010 census,  down from 519 at the 2000 census. It is situated north of the Homochitto River, which runs from the northeast to the southwest through the county on its way to its outlet at the Mississippi River.
It is home to a chess center, covered in 60 Minutes story aired March 26, 2017, involving chess coach Jeff Bulington. 
The town was named after Cowles Mead, a 19th-century political leader.  This town developed as a trading center for the agricultural county, which had an early economy based on the cultivation of cotton. Court days also attracted farmers and their customers. The county is still largely rural.
Meadville is located in the center of Franklin County at 31°28′23″N 90°53′27″W / 31.47306°N 90.89083°W (31.472998, -90.890856).  U.S. Routes 98 and 84 bypass the town to the south. U.S. 84 leads east 32 miles (51 km) to Brookhaven, and U.S. 98 leads southeast 36 miles (58 km) to McComb. Together the highways lead west 32 miles (51 km) to Natchez.
According to the United States Census Bureau, Meadville has a total area of 1.1 square miles (2.9 km2), all land. 
The town had its peak of population in 1960. As of the 2020 United States census, there were 448 people, 230 households, and 144 families residing in the town.
|U.S. Decennial Census |
|Black or African American (non-Hispanic)||70||15.63%|
|Hispanic or Latino||3||0.67%|
In 2000, the racial makeup of the town was 82.85% White, 15.41% African American, 0.77% Asian, and 0.96% from two or more races. Hispanic or Latino of any race were 0.58% of the population. By 2020, its racial and ethnic makeup was 80.13% non-Hispanic white, 15.63% African American, 0.45% Native American, 3.13% mixed, and 0.67% Hispanic or Latino of any race. 
Meadville is served by the Franklin County School District, which includes Franklin County Elementary and a host of day cares and headstarts.