Irish geneticist and professor
Aoife McLysaght is an Irish geneticist and a
professor in the
Molecular Evolution Laboratory of the Smurfit Institute of Genetics,
Trinity College Dublin in Ireland.
[1]
[3]
[4]
[5]
Education
McLysaght was educated at the
Trinity College Dublin where she was awarded a
Bachelor of Arts degree in
Genetics in 1998, followed by a
PhD in 2002 for research supervised by
Kenneth H. Wolfe on the
evolution of
vertebrate
genome organisation .
[2]
[6]
[7]
[8]
Career and research
Following her PhD, she completed
postdoctoral research at the
University of California, Irvine
[9] working with
Brandon Gaut before returning to work in Dublin in 2003. Her research in
molecular evolution and
comparative genomics
[1] has been published in leading
peer-reviewed scientific journals including
Nature ,
[10]
Nature Genetics ,
[11]
Bioinformatics ,
[12]
Genome Research ,
[13]
PNAS
[14]
[15] and the journal
Yeast .
[16]
She has served as senior editor and associate editor for the journals
Molecular Biology and Evolution and
Genome Biology and Evolution , and is on the
editorial board of the journal
Cell Reports . She is a member of the
Society for Molecular Biology and Evolution (SMBE) and
The Genetics Society .[
citation needed ] She served as Treasurer of SMBE 2012–14 and was elected President of the Society in 2017.
[17]
Outreach and media
McLysaght is a regular contributor to public events, and has spoken at IGNITE
Electric Picnic ,
[18]
[19]
TEDx , The
Royal Institution , and on the
BBC Radio 4 programme
The Infinite Monkey Cage .
[20] She brought genetics to a wider audience in the
Royal Institution 2013
advent calendar
[9] where she featured in videos on
human chromosome 1 ,
[21]
human chromosome 14 ,
[22]
mitochondrial DNA (mtDNA)
[23] and the
Science Gallery , Dublin. In 2018 she joined with
Alice Roberts to write and present the televised
Royal Institution Christmas Lectures .
[24]
Awards and honours
McLysaght was awarded
European Research Council (ERC) Consolidator Grant 2018–23 and an ERC Starting Researcher grant from 2013 to 2018, and the
President of Ireland Young Researcher's Award by
Science Foundation Ireland (SFI) in 2005.
[25]
[26] She gave the
J. B. S. Haldane lecture of
The Genetics Society in 2016.
[27] She was one of eight women scientists whose portrait was commissioned as part of the
Royal Irish Academy 's Women on Walls project.
[28]
In 2010 she was elected a fellow of Trinity College Dublin.
[29]
Personal life
McLysaght is a granddaughter of genealogist
Edward MacLysaght .
[30] McLysaght has two children, and a dog whose
genome has been sequenced .
[31]
References
^
a
b
c
d
Aoife McLysaght publications indexed by
Google Scholar
^
a
b McLysaght, Aoife (2002).
Evolution of vertebrate genome organisation (PDF) (PhD thesis). Trinity College Dublin.
OCLC
842498402 . Archived from
the original (PDF) on 6 November 2017.
^
Aoife McLysaght publications indexed by the
Scopus bibliographic database. (subscription required)
^
Aoife McLysaght at
DBLP Bibliography Server
^
Aoife McLysaght publications from
Europe PubMed Central
^ Aoife McLysaght's
ORCID
0000-0003-2552-6220
^ Wolfe, Ken (2017).
"Wolfe lab alumni" . wolfe.ucd.ie . Archived from
the original on 11 July 2017.
^
"Aoife McLysaght Academic Tree" . academictree.org .
^
a
b O’Connell, Claire (2014).
"Professor brings science to life with flair" . siliconrepublic.com .
^
Lander, Eric S. ; Linton, Lauren M.; Birren, Bruce; Nusbaum, Chad; Zody, Michael C.; Baldwin, Jennifer; Devon, Keri; Dewar, Ken; Doyle, Michael; FitzHugh, William; Funke, Roel; et al. (2001).
"Initial sequencing and analysis of the human genome" . Nature . 409 (6822): 860–921.
doi :
10.1038/35057062 .
hdl :
2027.42/62798 .
ISSN
0028-0836 .
PMID
11237011 .
^ McLysaght, Aoife; Hokamp, Karsten; Wolfe, Kenneth H. (2002). "Extensive genomic duplication during early chordate evolution". Nature Genetics . 31 (2): 200–204.
doi :
10.1038/ng884 .
ISSN
1061-4036 .
PMID
12032567 .
S2CID
8263376 .
^ Pollastri, G.; McLysaght, A. (2004).
"Porter: a new, accurate server for protein secondary structure prediction" (PDF) . Bioinformatics . 21 (8): 1719–1720.
doi :
10.1093/bioinformatics/bti203 .
ISSN
1367-4803 .
PMID
15585524 .
^ Knowles, D. G.; McLysaght, A. (2009).
"Recent de novo origin of human protein-coding genes" . Genome Research . 19 (10): 1752–1759.
doi :
10.1101/gr.095026.109 .
ISSN
1088-9051 .
PMC
2765279 .
PMID
19726446 .
^ McLysaght, A.; Baldi, P. F.; Gaut, B. S. (2003).
"Extensive gene gain associated with adaptive evolution of poxviruses" . Proceedings of the National Academy of Sciences . 100 (26): 15655–15660.
doi :
10.1073/pnas.2136653100 .
ISSN
0027-8424 .
PMC
307623 .
PMID
14660798 .
^ Makino, T.; McLysaght, A. (2010).
"Ohnologs in the human genome are dosage balanced and frequently associated with disease" . Proceedings of the National Academy of Sciences . 107 (20): 9270–9274.
doi :
10.1073/pnas.0914697107 .
ISSN
0027-8424 .
PMC
2889102 .
PMID
20439718 .
^ McLysaght, Aoife; Enright, Anton J.; Skrabanek, Lucy; Wolfe, Kenneth H. (2000).
"Estimation of Synteny Conservation and Genome Compaction Between Pufferfish (Fugu) and Human" . Yeast . 1 (1): 22–36.
doi :
10.1002/(SICI)1097-0061(200004)17:1<22::AID-YEA5>3.0.CO;2-S .
ISSN
0749-503X .
PMC
2447035 .
PMID
10797599 .
^
"SMBE Council" . smbe.org . Society for Molecular Biology & Evolution. 2019. Retrieved 21 January 2019 .
^
"Aoife McLysaght at IGNITE Dublin #1" . youtube.com .
YouTube .
^
"Aoife McLysaght at IGNITE at Electric Picnic" . youtube.com .
YouTube .
^
"Alfred Russel Wallace: The Infinite Monkey Cage, Series 8 Episode 5 of 6" . bbc.co.uk .
BBC .
^
"Chromosome 1 – The Stuff of Life" . youtube.com .
YouTube .
^
"Chromosome 14 – Immunoglobulins: building our immune system" . youtube.com .
YouTube .
^
"Chromosome 24 – mtDNA, Lynn Margulis and the mitochondrial DNA" . youtube.com .
YouTube .
^
"CHRISTMAS LECTURES 2018: Who am I?" . rigb.org . Royal Institution. Archived from
the original on 23 October 2019. Retrieved 27 December 2018 .
^
"Professor Aoife Mclysaght" . accenture.com .
Accenture .
^
"Trinity Research: Professor Aoife McLysaght" . tcd.ie .
^
"JBS Haldane Lecture – Genetics Society" . genetics.org.uk .
^
"Women on Walls" . www.ria.ie . Royal Irish Academy. 2016. Retrieved 26 December 2020 .
^
"Trinity Monday 2010 - Fellows and Scholars" . www.tcd.ie . Trinity College Dublin. 12 April 2010. Retrieved 1 July 2023 .
^ McLysaght, Aoife (2014).
"The genetic imprint of Niall of the Nine Hostages" . irishtimes.com . The Irish Times.
^
"Cara Genome Project (@CaraGenome) | Twitter" . twitter.com .
International National Academics