The function of this receptor is still poorly understood, but it is thought to have roles in many disorders such as
pain,
drug addiction, development of tolerance to
opioid drugs, and
psychological disorders such as
anxiety and
depression. Research into the function of this receptor is an important focus of current
pharmaceutical development, and selective agents such as NNC 63-0532 are essential for this work.[3]
^Chiou LC, Liao YY, Fan PC, Kuo PH, Wang CH, Riemer C, Prinssen EP (January 2007). "Nociceptin/orphanin FQ peptide receptors: pharmacology and clinical implications". Current Drug Targets. 8 (1): 117–35.
doi:
10.2174/138945007779315605.
PMID17266536.